Literature DB >> 3561401

Cell cycle-dependent effects on deoxyribonucleotide and DNA labeling by nucleoside precursors in mammalian cells.

J M Leeds, C K Mathews.   

Abstract

dCTP pools equilibrated to equivalent specific activities in Chinese hamster ovary cells or in nuclei after incubation of cells with radiolabeled nucleosides, indicating that dCTP in nuclei does not constitute a distinct metabolic pool. In the G1 phase, [5-3H]deoxycytidine labeled dCTP to unexpectedly high specific activities. This may explain reports of replication-excluded DNA precursor pools.

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Year:  1987        PMID： 3561401      PMCID： PMC365098          DOI： 10.1128/mcb.7.1.532-534.1987

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  19 in total

1.  Effects of arabinosyl-cytosine on thymidine triphosphate pools and polyoma DNA replication.

Authors:  D Hellgren; S Nilsson; P Reichard
Journal:  Biochem Biophys Res Commun       Date:  1979-05-14       Impact factor: 3.575

2.  DNA precursors in eukaryotic cells.

Authors:  A Fridland
Journal:  Nat New Biol       Date:  1973-05-23

3.  In vivo rates of pyrimidine nucleotide metabolism in intact mouse T-lymphoma (s-49) cells treated with 5-fluorouracil.

Authors:  J Maybaum; M B Cohen; W Sadee
Journal:  J Biol Chem       Date:  1981-03-10       Impact factor: 5.157

4.  Detection of activities that interfere with the enzymatic assay of deoxyribonucleoside 5'-triphosphates.

Authors:  T W North; R K Bestwick; C K Mathews
Journal:  J Biol Chem       Date:  1980-07-25       Impact factor: 5.157

5.  Isotope-dilution analysis of the effects of deoxyguanosine and deoxyadenosine on the incorporation of thymidine and deoxycytidine by hydroxyurea-treated thymus cells.

Authors:  F W Scott; D R Forsdyke
Journal:  Biochem J       Date:  1980-09-15       Impact factor: 3.857

6.  Changes in ribo- and deoxyribonucleoside triphosphate pools within the cell cycle of a synchronized mouse fibroblast cell line.

Authors:  P J McCormick; L L Danhauser; Y M Rustum; J S Bertram
Journal:  Biochim Biophys Acta       Date:  1983-03-15

7.  Reduced rate of DNA replication fork movement in megaloblastic anemia.

Authors:  R G Wickremasinghe; A V Hoffbrand
Journal:  J Clin Invest       Date:  1980-01       Impact factor: 14.808

8.  Comparison of purine and pyrimidine metabolism in G1 and S phases of HeLa and Chinese hamster ovary cells.

Authors:  J Hordern; J F Henderson
Journal:  Can J Biochem       Date:  1982-04

9.  Determination of deoxyribonucleoside triphosphates using DNA polymerase: a critical evaluation.

Authors:  D Hunting; J F Henderson
Journal:  Can J Biochem       Date:  1981-09

10.  DNA precursor pools and ribonucleotide reductase activity: distribution between the nucleus and cytoplasm of mammalian cells.

Authors:  J M Leeds; M B Slabaugh; C K Mathews
Journal:  Mol Cell Biol       Date:  1985-12       Impact factor: 4.272
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  6 in total

1.  Temperature-sensitive DNA mutant of Chinese hamster ovary cells with a thermolabile ribonucleotide reductase activity.

Authors:  B E Wojcik; J J Dermody; H L Ozer; B Mun; C K Mathews
Journal:  Mol Cell Biol       Date:  1990-11       Impact factor: 4.272

2.  Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector.

Authors:  U Blömer; L Naldini; T Kafri; D Trono; I M Verma; F H Gage
Journal:  J Virol       Date:  1997-09       Impact factor: 5.103

3.  Guanine for DNA synthesis. A compulsory route through ribonucleotide reductase.

Authors:  D S Duan; W Sadee
Journal:  Biochem J       Date:  1988-11-01       Impact factor: 3.857

4.  Cell cycle-dependent variations in deoxyribonucleotide metabolism among Chinese hamster cell lines bearing the Thy- mutator phenotype.

Authors:  B J Mun; C K Mathews
Journal:  Mol Cell Biol       Date:  1991-01       Impact factor: 4.272

5.  Increasing transduction efficiency of recombinant murine retrovirus vectors by initiation of endogenous reverse transcription: potential utility for genetic therapies.

Authors:  H Zhang; L X Duan; G Dornadula; R J Pomerantz
Journal:  J Virol       Date:  1995-06       Impact factor: 5.103

6.  Discovery of a novel DNA polymerase inhibitor and characterization of its antiproliferative properties.

Authors:  Bhanvi Mishra; Sufang Zhang; Hong Zhao; Zbigniew Darzynkiewicz; Ernest Y C Lee; Marietta Y W T Lee; Zhongtao Zhang
Journal:  Cancer Biol Ther       Date:  2018-11-14       Impact factor: 4.742
  6 in total

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