Literature DB >> 35612382

Prior Involvement of Central Motor Drive Does Not Impact Performance and Neuromuscular Fatigue in a Subsequent Endurance Task.

Fabio Giuseppe Laginestra1, Alessandro Cavicchia1, Jennifer E Vanegas-Lopez2, Chiara Barbi1, Camilla Martignon1, Gaia Giuriato1, Anna Pedrinolla1, Markus Amann3, Thomas J Hureau2, Massimo Venturelli1.   

Abstract

PURPOSE: This study evaluated whether central motor drive during fatiguing exercise plays a role in determining performance and the development of neuromuscular fatigue during a subsequent endurance task.
METHODS: On separate days, 10 males completed three constant-load (80% peak power output), single-leg knee-extension trials to task failure in a randomized fashion. One trial was performed without preexisting quadriceps fatigue (CON), and two trials were performed with preexisting quadriceps fatigue induced either by voluntary (VOL; involving central motor drive) or electrically evoked (EVO; without central motor drive) quadriceps contractions (~20% maximal voluntary contraction (MVC)). Neuromuscular fatigue was assessed via pre-post changes in MVC, voluntary activation (VA), and quadriceps potentiated twitch force ( Qtw,pot ). Cardiorespiratory responses and rating of perceived exertion were also collected throughout the sessions. The two prefatiguing protocols were matched for peripheral fatigue and stopped when Qtw,pot declined by ~35%.
RESULTS: Time to exhaustion was shorter in EVO (4.3 ± 1.3 min) and VOL (4.7 ± 1.5 min) compared with CON (10.8 ± 3.6 min, P < 0.01) with no difference between EVO and VOL. ΔMVC (EVO: -47% ± 8%, VOL: -45% ± 8%, CON: -53% ± 8%), Δ Qtw,pot (EVO: -65% ± 7%, VOL: -59% ± 14%, CON: -64% ± 9%), and ΔVA (EVO: -9% ± 7%, VOL: -8% ± 5%, CON: -7% ± 5%) at the end of the dynamic task were not different between conditions (all P > 0.05). Compared with EVO (10.6 ± 1.7) and CON (6.8 ± 0.8), rating of perceived exertion was higher ( P = 0.05) at the beginning of VOL (12.2 ± 1.0).
CONCLUSIONS: These results suggest that central motor drive involvement during prior exercise plays a negligible role on the subsequent endurance performance. Therefore, our findings indicate that peripheral fatigue-mediated impairments are the primary determinants of high-intensity single-leg endurance performance.
Copyright © 2022 by the American College of Sports Medicine.

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Mesh:

Year:  2022        PMID: 35612382      PMCID: PMC9481724          DOI: 10.1249/MSS.0000000000002965

Source DB:  PubMed          Journal:  Med Sci Sports Exerc        ISSN: 0195-9131


  49 in total

1.  Time course of human motoneuron recovery after sustained low-level voluntary activity.

Authors:  Martin E Héroux; Annie A Butler; Simon C Gandevia; Janet L Taylor; Jane E Butler
Journal:  J Neurophysiol       Date:  2015-11-25       Impact factor: 2.714

2.  Less peripheral fatigue after prior exercise is not evidence against the regulation of the critical peripheral fatigue threshold.

Authors:  Ryan M Broxterman; Russell S Richardson; Markus Amann
Journal:  J Appl Physiol (1985)       Date:  2015-12-15

3.  Fatigue-related group III/IV muscle afferent feedback facilitates intracortical inhibition during locomotor exercise.

Authors:  Simranjit K Sidhu; Joshua C Weavil; Taylor S Thurston; Dorothea Rosenberger; Jacob E Jessop; Eivind Wang; Russell S Richardson; Chris J McNeil; Markus Amann
Journal:  J Physiol       Date:  2018-09-03       Impact factor: 5.182

4.  Pharmacological attenuation of group III/IV muscle afferents improves endurance performance when oxygen delivery to locomotor muscles is preserved.

Authors:  Thomas J Hureau; Joshua C Weavil; Taylor S Thurston; Hsuan-Yu Wan; Jayson R Gifford; Jacob E Jessop; Michael J Buys; Russell S Richardson; Markus Amann
Journal:  J Appl Physiol (1985)       Date:  2019-09-12

Review 5.  Power-duration relationship: Physiology, fatigue, and the limits of human performance.

Authors:  Mark Burnley; Andrew M Jones
Journal:  Eur J Sport Sci       Date:  2016-11-03       Impact factor: 4.050

6.  Supraspinal factors in human muscle fatigue: evidence for suboptimal output from the motor cortex.

Authors:  S C Gandevia; G M Allen; J E Butler; J L Taylor
Journal:  J Physiol       Date:  1996-01-15       Impact factor: 5.182

7.  Impact of preinduced quadriceps fatigue on exercise response in chronic obstructive pulmonary disease and healthy subjects.

Authors:  Philippe Gagnon; Didier Saey; Isabelle Vivodtzev; Louis Laviolette; Vincent Mainguy; Julie Milot; Steeve Provencher; François Maltais
Journal:  J Appl Physiol (1985)       Date:  2009-07-02

8.  Mechanisms of Fatigue and Recovery in Upper versus Lower Limbs in Men.

Authors:  Gianluca Vernillo; John Temesi; Matthieu Martin; Guillaume Y Millet
Journal:  Med Sci Sports Exerc       Date:  2018-02       Impact factor: 5.411

9.  Fatiguing Neuromuscular Electrical Stimulation Decreases the Sense of Effort During Subsequent Voluntary Contractions in Men.

Authors:  Florian Monjo; Raphael Zory; Nicolas Forestier
Journal:  Neuroscience       Date:  2020-09-04       Impact factor: 3.590

Review 10.  New insights into corollary discharges mediated by identified neural pathways.

Authors:  James F A Poulet; Berthold Hedwig
Journal:  Trends Neurosci       Date:  2006-11-29       Impact factor: 13.837

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