Dear Editor,We would like to share ideas on the publication “Time-related aortic inflammatory response, as assessed with 18F-FDG PET/CT, in patients hospitalized with severely or critical COVID-19: the COVAIR study.[1] ” Aortic inflammation, as measured by 18F-FDG PET/CT imaging in patients with severe or critical COVID-19, is enhanced in the early post COVID phase and essentially decreases over time, according to Vlachopoulos et al.[1]. We agree that COVID-19 may have an inflammatory alteration in the aorta. During COVID-19, the pathophysiology could be attributable to an aberrant inflammatory response or a hyperviscosity process.[2] The recent report suggests that the process is reversible and that no pathophysiological process via a permanent pathoimmunological mechanism exists.