| Literature DB >> 35607489 |
Kimberley L Way1,2, David Birnie3, Christopher Blanchard4, George Wells5, Paul Dorian6, Harald T Jorstad7, Ioana C Daha8, Neville Suskin9, Paul Oh10, Ratika Parkash4, Paul Poirier11, Stephanie A Prince12,5, Heather Tulloch13,14, Andrew L Pipe13,14, Harleen Hans1, Janet Wilson1,14, Katelyn Comeau1,15, Sol Vidal-Almela1,15,16, Tasuku Terada1, Jennifer L Reed1,5,15.
Abstract
Background: The primary goal of this study was to determine the time spent completing moderate-to-vigorous intensity physical activity (MVPA) among adults with atrial fibrillation (AF). Secondary aims examined MVPA and sitting time (ST) by AF subtypes (ie, paroxysmal, persistent, long-standing persistent, and permanent) and associations between MVPA or ST and knowledge, task self-efficacy, and outcome expectations.Entities:
Year: 2022 PMID: 35607489 PMCID: PMC9123363 DOI: 10.1016/j.cjco.2022.01.004
Source DB: PubMed Journal: CJC Open ISSN: 2589-790X
Figure 1Consolidated Standards of Reporting Trials (CONSORT) diagram.
Participant characteristics
| Cohort | Paroxysmal [n = 283] | Persistent [n = 90] | Long-standing persistent [n = 10] | Permanent [n = 43] | ||
|---|---|---|---|---|---|---|
| Age, y | 65 (64–67) [605] | 66 (63–68) [276] | 65 (61–67) [88] | 77 (73–80) | 68 (60–73) [42] | |
| Length of diagnosis, y | 8 (8-9) [558] | 8 (7-8) [258] | 7 (6-9) [88] | 7 (3-13) [8] | 13 (10-16) [38] | |
| Sex, male | 408 (66) [616] | 174 (62) [283] | 71 (81) [88] | 6 (60) | 37 (86) | |
| Gender, men | 409 (66) | 174 (62) [283] | 72 (81) | 6 (60) | 37 (86) | |
| Ethnicity, British | 305 (50) [615] | 143 (51) [281] | 42 (47) | 5 (50) | 27 (63) | 0.407 |
| Marital status, married | 487 (79) [619] | 230 (81) [283] | 76 (84) [90] | 6 (60) | 33 (77) | |
| Live with spouse, | 492 (80) [615] | 231 (83) [279] | 79 (88) [90] | 5 (50) | 33 (77) | |
| Education, university —undergraduate | 159 (26) [616] | 75 (27) | 32 (36) | 2 (20) | 11 (26) [42] | |
| Employment status, retired | 423 (68) [618] | 189 (67) | 59 (66) [90] | 8 (80) | 31 (72) | 0.908 |
| Income, $50,000–$74,999 | 138 (24) [588] | 66 (25) [265 | 16 (19) [86] | 2 (22) [9] | 13 (31) [42] | 0.052 |
| Smoker | 34 (6) [615] | 13 (5) [283] | 4 (4) [90] | 0 (0) | 1 (2) [42] | 0.826 |
| BMI, kg/m2 | 28.8 (28.2–29.4) [585] | 27.9 (27.3–28.9) [270] | 31.0 (29.1–32.6) [82] | 28.6 (26.3–33.0) [9] | 31.7 (29.0–33.7) [41] | |
| AF control | 418 (69) [609] | 182 (66) [278] | 66 (75) [88] | 8 (80) | 28 (67) [42] | 0.675 |
| Anti-coagulants/anti-thrombotics | 508 (83) [616] | 223 (79) [283] | 75 (86) [87] | 8 (80) | 41 (95) | 0.177 |
| Catheter ablation | 260 (43) [612] | 126 (45) [281] | 52 (58) | 1 (10) | 15 (36) [42] | |
| Hypertension | 292 (47) | 126 (45) | 37 (42) | 3 (30) | 20 (47) | 0.760 |
| Angina | 23 (4) | 13 (5) | 2 (2) | 0 (0) | 0 (0) | 0.344 |
| Prediabetes | 44 (7) | 17 (6) | 8 (9) | 1 (10) | 3 (7) | 0.188 |
| Type 1 diabetes | 3 (1) [616] | 0 (0) | 0 (0) | 0 (0) | 1 (2) | |
| Type 2 diabetes | 66 (11) | 27 (10) | 7 (8) | 0 (0) | 5 (12) | 0.670 |
| Overweight/obese | 110 (18) | 48 (17) | 17 (19) | 1 (10) | 7 (16) | 0.892 |
| Chronic kidney disease | 27 (4) | 9 (3) | 2 (2) | 1 (10) | 2 (5) | 0.578 |
| Heart failure | 79 (13) | 20 (7) | 9 (10) | 5 (50) | 11 (26) | |
| Hypercholesterolemia | 168 (27) | 70 (25) | 33 (37) | 0 (0) | 10 (23) | |
| Cardiomyopathy | 58 (9) | 26 (9) | 4 (5) | 2 (20) | 5 (12) | 0.247 |
| Heart block | 11 (2) [616] | 3 (1) | 1 (1) | 0 (0) | 0 (0) | 0.901 |
| Coronary heart disease | 61 (10) | 26 (9) | 5 (6) | 2 (20) | 4 (9) | 0.427 |
| COPD | 23 (4) [616] | 6 (2) | 3 (3) | 1 (11) [9] | 3 (7) | 0.170 |
| Pulmonary hypertension | 8 (1) | 3 (1) | 2 (2) | 0 (0) | 0 (0) | 0.674 |
| Valvular heart disease | 54 (9) [618] | 15 (5) | 6 (7) [90] | 2 (20) | 3 (7) | 0.287 |
| Rheumatic fever | 12 (2) | 4 (1) | 1 (1) | 1 (10) | 1 (2) | 0.198 |
| Anxiety | 67 (11) | 37 (13) | 3 (3) | 1 (10) | 4 (9) | 0.076 |
| Depression | 50 (8) | 32 (11) | 1 (1) | 1 (10) | 1 (2) | |
| Sleep apnea | 148 (24) | 66 (23) | 24 (27) | 3 (30) | 14 (33) | 0.576 |
Values are presented as median (95% CI) or n (%). Values in square brackets are overall [n] for category. Fisher’s exact test was used in instances where > 20% of cells had an expected count of < 5. Boldface indicates significance.
AF, atrial fibrillation; BMI, body mass index; CI, confidence interval; COPD, chronic obstructive pulmonary disorder.
Includes data of individuals with unknown AF subtype.
P value reported examines the statistical difference between AF subtypes.
Significant difference among AF subtypes (P < 0.05).
Significant difference among AF subtypes (P < 0.01).
Physical activity (PA) and cardiorespiratory fitness (CRF) outcomes
| Physical activity/cardiorespiratory fitness outcomes | Cohort | NR, mean (SD) | Paroxysmal | Persistent | Long-standing persistent | Permanent | |
|---|---|---|---|---|---|---|---|
| Walking | 240 (170–270) [222] | 294 (298) [222] | 270 (135–294) [107] | 240 (80–360) [34] | 495 (84–777) [4] | 135 (0–450) [13] | 0.603 |
| Moderate-intensity PA | 60 (40–90) [513] | 139 (193) [513] | 45 (8–80) [239] | 90 (30–180) [73] | 10 (0–113) [6] | 40 (0–135) [37] | 0.156 |
| Vigorous-intensity PA | 0 (0–0) [554] | 66 (130) [63] | 0 (0–0) [259] | 0 (0–0) [80] | 90 (0–180) [4] | 0 (0–0) [40] | 0.571 |
| Total MVPA | 100 (60–120) [498] | 185 (228) [498] | 68 (30–120) [230] | 180 (60–270) [73] | 60 (0–360) [5] | 60 (30–165) [37] | 0.151 |
| Total sitting time, h/d | 6 (5–6) [487] | 6 (4) [487] | 5 (5–6) [223] | 6 (5–6) [72] | 6 (4–7) [9] | 5 (4–7) [37] | 0.955 |
| V̇O2peak, mL/kg/min | 27.6 (26.8–30.0) [555] | 26.2 (7.0) [555] | 28.0 (26.8–30.2) [261] | 27.6 (24.4–30.2) [79] | 21.4 (18.5–30.2) [9] | 27.8 (18.8–30.2) [39] | 0.282 |
| METs | 7.9 (7.7–8.6) [555] | 7.5 (2.0) [555] | 8.0 (7.7–8.6) [261] | 7.9 (7.0–8.6) [79] | 6.1 (5.3–8.6) [9] | 7.9 (5.4–8.6) [39] | 0.282 |
Values are reported as median (95% confidence interval), in minutes per week, unless otherwise noted. Overall [n] for category is given in square brackets. Atrial fibrillation (AF) subtype (if available) was extracted for each patient from their medical chart.
MET, metabolic equivalent; MVPA, moderate-to-vigorous physical activity; NR, not reported; V̇O2peak, peak oxygen uptake.
Includes data with unknown AF subtypes.
P value reported examines the difference across all AF subtypes.
Knowledge, values, outcome expectation, and task self-efficacy regarding physical activity and symptom severity and quality-of-life outcomes
| Cohort | Paroxysmal | Persistent | Long-standing persistent | Permanent | ||
|---|---|---|---|---|---|---|
| “Has a healthcare professional (doctor, cardiologist, nurse etc.) spoken to you about engaging in physical activity to manage your irregular heart rhythm?” {No} | 358 (59) [604] | 160 (58) [277] | 53 (61) [87] | 3 (30) [10] | 27 (63) [43] | 0.269 |
| “How much physical activity such as walking, swimming, bicycling is recommended per week?” {I don’t know/unsure} | 303 (54) [563] | 134 (52) [257] | 47 (58) [81] | 6 (60) [10] | 26 (62) [42] | 0.978 |
| “How many days per week should people should be engaged in physical activity such as walking, swimming, bicycling?” {I don’t know/unsure} | 143 (25) [569] | 62 (24) [261] | 26 (32) [81] | 3 (30) [10] | 10 (24) [42] | 0.625 |
| “How often should people perform muscle strengthening based exercise per week?” {I don’t know/unsure} | 237 (42) [570] | 118 (45) [262] | 33 (41) [81] | 4 (40) [10] | 17 (40) [43] | 0.540 |
| “Can physical activity help manage other conditions you may have (ie, diabetes, high blood pressure, high cholesterol)?” {Yes} | 464 (81) [576] | 218 (82) [265] | 62 (76) [82] | 7 (88) [8] | 31 (76) [41] | 0.802 |
| “Do you think physical activity is dangerous for your irregular heart rhythm?” {No} | 376 (66) [570] | 160 (64) [250] | 50 (63) [80] | 8 (80) [10] | 29 (69) [42] | 0.367 |
| “Do you think physical activity should be a part of your management plan for your irregular heart rhythm?” {Yes} | 416 (72) [577] | 193 (73) [264] | 55 (67) [82] | 10 (100) [10] | 33 (79) [42] | 0.251 |
| “It is really not safe to be physically active with my irregular heart rhythm if my heart rate becomes too fast.” {Disagree} | 230 (40) [573] | 112 (43) [263] | 28 (34) [82] | 7 (78) [9] | 18 (43) [42] | 0.467 |
| “No one should have to be physically active when he/she has my irregular heart rhythm.” {Disagree} | 304 (53) [578] | 130 (49) [264] | 42 (51) [82] | 6 (67) [9] | 25 (60) [42] | 0.624 |
| “How important do you think physical activity is for managing your irregular heart rhythm?” {Important} | 218 (38) [569] | 95 (36) [261] | 31 (38) [81] | 3 (33) [9] | 16 (37) [43] | 0.976 |
| “How important do you think physical activity is for managing other conditions you may have (ie, diabetes, high blood pressure, high cholesterol, overweight/obesity)?” {Important} | 244 (43) [569] | 107 (43) [250] | 32 (40) [80] | 5 (50) [10] | 17 (42) [41] | 0.965 |
| “If I tried to be physically active my irregular heart rhythm would worsen.” {Disagree} | 291 (50) [579] | 133 (50) [264] | 38 (46) [82] | 6 (60) [10] | 17 (40) [43] | 0.743 |
| “My irregular heart rhythm would improve if I was physically active.” {Agree} | 250 (44) [563] | 118 (46) [258] | 37 (46) [80] | 1 (11) [9] | 17 (40) [43] | 0.075 |
| “I would manage my irregular heart rhythm better if I was physically active.” {Agree} | 283 (50) [562] | 126 (49) [259] | 42 (53) [79] | 4 (50) [8] | 19 (45) [42] | 0.577 |
| “Do you consider yourself physically active?” {Yes} | 332 (58) [574] | 151 (58) [260] | 53 (65) [82] | 4 (40) [10] | 23 (54) [43] | 0.370 |
| “Do you do light physical activity?” {Yes} | 308 (59) [520] | 144 (59)[244 | 45 (58) [78] | 5 (83)[6 | 22 (61)[36 | 0.665 |
| “Do you do moderate physical activity?” {Yes} | 291 (56) [520] | 130 (53) [244] | 46 (59) [78] | 5 (83) [6] | 19 (53) [36] | 0.422 |
| “Do you do vigorous physical activity?” {No} | 452 (87) [520] | 212 (87)[244 | 67 (86) [78] | 5 (83) [6] | 33 (92) [36] | 0.837 |
| “Do you do interval training?” {No} | 471 (91) [520] | 223 (91) [244] | 67 (86) [78] | 5 (83) [6] | 36 (100) [36] | 0.091 |
| “Do you do muscle strengthening physical activity?” {No} | 406 (78) [519] | 192 (79) [244] | 60 (77) [78] | 5 (83) [6] | 31 (86) [36] | 0.709 |
| “How confident do you feel performing light physical activity?” {Very confident} | 202 (37) [542] | 94 (38) [246] | 32(41) [78] | 3 (38) [8] | 13 (33) [40] | 0.435 |
| “How confident do you feel performing moderate physical activity?” {Very confident} | 118 (22) [538] | 52 (21) [243] | 22 (29) [77] | 1 (13) [8] | 10 (25) [40] | 0.467 |
| “How confident do you feel performing vigorous physical activity?” {Not confident} | 187 (34) [544] | 88 (36) [245] | 29 (36) [80] | 0 (0) [8] | 14 (35) [40] | 0.462 |
| “How confident do you feel performing interval training?” {Neutral} | 162 (28) [576] | 83 (32) [263] | 18 (22) [81] | 3 (30) [10] | 13 (30) [43] | 0.558 |
| “How confident do you feel performing muscle strengthening activity?” {Neutral} | 171 (30) [573] | 77 (30) [261] | 28 (34) [83] | 3 (33) [9] | 13 (31) [42] | 0.990 |
| Frequency score | 3 (3–4) [595] | 3 (3–3) [269 | 4 (3–8) [88] | 4 (0–10) [10] | 10 (7–10) [42] | |
| Duration score | 5 (4–6) [590] | 5 (4–7)[264] | 7 (7–10) [88] | 3 (2–10) [10] | 10 (3–10) [40] | |
| Severity score | 5 (5–6) [565] | 6 (5–6) [261] | 5 (4–6) [83] | 2 (1–6) [9] | 3 (2–5) [39] | |
| Total burden score | 15 (15–16) [546] | 15 (14–16) [246 | 18 (16–20) [83] | 19 (3–23) [9] | 21 (18–22) [38] | |
| Hospital visits | 0 (0–0) [605] | 0 (0–0) [275 | 0 (0–0) [88] | 0 (0–0) [10] | 0 (0–0) [42] | 0.658 |
| Specialist visits | 0 (0–0) [600] | 0 (0–1) [274] | 0 (0–1) [88] | 1 (0–2) [10] | 0 (0–1) [42] | 0.660 |
| Emergency room visits | 0 (0–0) [598] | 0 (0–0) [273] | 0 (0–0) [88] | 0 (0–1) [10] | 0 (0–0) [42] | 0.077 |
| Bothered by symptoms | 5 (5–6) [595] | 4 (4–5) [272] | 6 (5–7) [87] | 7 (4–14) [9] | 4 (3–6) [41] | 0.152 |
| Symptom score | 89 (89–89) [593] | 89 (89–89) [270] | 89 (83–94) [86] | 89 (78–100) [10] | 92 (89–94) [40] | 0.377 |
| Daily activities score | 76 (74–76) [568] | 76 (74–81) [258] | 76 (68–81) [84] | 57 (31–81) [9] | 69 (62–86) [41] | 0.120 |
| Treatment control | 83 (83–83) [596] | 83 (83–83) [272] | 83 (67–83) [86] | 83 (50–100) [9] | 83 (67–92) [43] | 0.879 |
| Total score | 83 (81–85) [588] | 83 (81–86) [263] | 83 (72–86) [85] | 86 (57–100) [10] | 86 (81–90) [43] | 0.534 |
Responses with the highest proportion are reported. Values are n (%), or median (95% confidence interval), with overall [n] for category in square brackets, unless otherwise noted. Boldface indicates significance.
AF, atrial fibrillation.
Includes data with unknown AF subtypes.
P value reported examines the statistical significance in the correlation between the variables.
Significant difference between AF subtypes (P < 0.01).
Correlation analyses for knowledge, values, outcome expectations, and task self-efficiacy regarding physical activity (PA) and PA levels or sedentary behaviour
| Survey questions | Total MVPA (ρ) | Total moderate-intensity PA (ρ) | Total vigorous-intensity PA (ρ) | Total sitting time (ρ) | ||||
|---|---|---|---|---|---|---|---|---|
| “Has a healthcare professional (doctor, cardiologist, nurse etc.) spoken to you about engaging in physical activity to manage your irregular heart rhythm?” {Yes} | 0.108 [493] | 0.103 [508] | 0.123 [547] | 0.049 [597] | 0.236 | |||
| “How much physical activity such as walking, swimming, bicycling is recommended per week?” {150 minutes per week} | 0.207 [456] | 0.197 [469] | 0.139 [507] | 0.014 [558] | 0.744 | |||
| “How often should people perform muscle strengthening based exercise per week?” {2 days per week} | –0.151 [460] | –0.124 [475] | –0.182 [514] | –0.020 [565] | 0.633 | |||
| “Can physical activity help manage other conditions you may have (ie, diabetes, high blood pressure, high cholesterol)?” {No} | –0.112 [465] | –0.090 [479] | –0.086 [520] | 0.051 | 0.062 [571] | 0.138 | ||
| “Do you think physical activity is dangerous for your irregular heart rhythm?” {No} | –0.037 [460] | 0.429 | –0.014 [473] | 0.768 | –0.025 [515] | 0.568 | –0.109 [449] | – |
| “Do you think physical activity should be a part of your management plan for your irregular heart rhythm?” {Yes} | –0.088 [462] | 0.057 | –0.104 [477] | –0.102 [518] | 0.076 [572] | 0.068 | ||
| “It is really not safe to be physically active with my irregular heart rhythm if my heart rate becomes too fast.” {Disagree} | –0.153 [465] | –0.102 [480] | –0.245 [517] | 0.081 [568] | 0.053 | |||
| “No one should have to be physically active when he/she has my irregular heart rhythm.” {Disagree} | –0.206 [468] | –0.174 [484] | –0.244 [521] | 0.010 [573] | 0.816 | |||
| “How important do you think physical activity is for managing your irregular heart rhythm?” {Important} | 0.232 [460] | 0.201 [475] | 0.280 [514] | –0.048 [475] | 0.301 | |||
| “How important do you think physical activity is for managing other conditions you may have (ie, diabetes, high blood pressure, high cholesterol, overweight/obesity)?” {Little importance} | 0.036 [465] | 0.433 | 0.054 [478] | 0.238 | 0.013 [514] | 0.776 | –0.010 [448] | 0.827 |
| “If I tried to be physically active my irregular heart rhythm would worsen.” {Disagree} | –0.256 [468] | –0.200 [483] | –0.329 [521] | 0.106 [574] | ||||
| “My irregular heart rhythm would improve if I was physically active.” {Agree} | 0.198 [457] | 0.178 [472] | 0.191 [509] | –0.090 [559] | ||||
| “I would manage my irregular heart rhythm better if I was physically active.” {Agree} | 0.205 [459] | 0.188 [470] | 0.219 [511] | –0.110 [558] | ||||
| “How confident do you feel performing light physical activity?” {Confident} | 0.342 [439] | 0.247 [454] | 0.396 [485] | –0.037 [538] | 0.391 | |||
| “How confident do you feel performing moderate physical activity?” {Confident} | 0.425 [435] | 0.304 [450] | 0.500 [481] | –0.091 [534] | 0.037 | |||
| “How confident do you feel performing vigorous physical activity?” {Confident} | 0.401 [442] | 0.261 [457] | 0.538 [488] | –0.109 [540] | ||||
| “How confident do you feel performing interval training?” {Confident} | 0.312 [467] | 0.211 [480] | 0.392 [521] | –0.072 [571] | ||||
| “How confident do you feel performing muscle strengthening activity?” {Confident} | 0.421 [465] | 0.323 [477] | 0.447 [519] | –0.124 [568] | ||||
| Frequency score | 0.040 [480] | 0.380 | 0.035 [491] | 0.439 | –0.005 [534] | 0.899 | –0.061 [590] | 0.141 |
| Duration score | 0.086 [476] | 0.060 | 0.085 [487] | 0.061 | 0.024 [529] | 0.584 | –0.022 [587] | 0.594 |
| Severity score | –0.028 [457] | 0.549 | 0.004 [469] | 0.931 | –0.044 [507] | 0.328 | 0.112 [562] | |
| Total burden score | 0.014 [444] | 0.768 | 0.035 [452] | 0.455 | –0.031 [491] | 0.495 | –0.012 [544] | 0.788 |
| Hospital visits | –0.020 [485] | 0.653 | –0.039 [500] | 0.382 | –0.025 [541] | 0.557 | 0.002 [599] | 0.952 |
| Specialist visits | –0.007 [482] | 0.878 | –0.003 [497] | 0.948 | –0.009 [537] | 0.842 | 0.015 [594] | 0.714 |
| Emergency room visits | –0.118 [477] | –0.106 [492] | –0.065 [533] | 0.132 | 0.034 [592] | 0.413 | ||
| Bothered by symptoms | –0.113 [480] | –0.085 [493] | 0.060 | –0.172 [534] | 0.064 [589] | 0.123 | ||
| Symptom score | 0.109 [477] | 0.082 [490] | 0.071 | 0.155 [531] | –0.039 [586] | 0.352 | ||
| Daily activities score | 0.305 [458] | 0.220 [472] | 0.372 [507] | –0.052 [561] | 0.222 | |||
| Treatment control | 0.127 [476] | 0.086 [491] | 0.057 | 0.182 [531] | –0.89 [589] | |||
| Total score | 0.136 [473] | 0.108 [489] | 0.184 [526] | –0.067 [581] | 0.108 | |||
Boldface indicates significance. Overall [n] for category is given in square brackets.
MVPA, moderate-to-vigorous PA.
P value reported examines the statistical significance in the correlation between the variables.
Denotes significant association (P < 0.05).
Denotes significant association (P < 0.01).
Figure 2(A) Proportion of self-reported responses for task self-efficacy for different intensities and mode of physical activity (PA). (B) Proportion of self-reported responses for outcome expectations regarding PA. (C) Proportion of self-report responses to knowledge and value questions regarding PA and atrial fibrillation (AF). HR, heart rate.