Literature DB >> 35604744

The effect of stimulant medication on the learning of academic curricula in children with ADHD: A randomized crossover study.

William E Pelham3, Amy R Altszuler2, Brittany M Merrill3, Joseph S Raiker3, Fiona L Macphee3, Marcela Ramos3, Elizabeth M Gnagy2, Andrew R Greiner2, Erika K Coles3, Carol M Connor4, Christopher J Lonigan3, Lisa Burger2, Anne S Morrow3, Xin Zhao3, James M Swanson5, James G Waxmonsky1, William E Pelham3.   

Abstract

OBJECTIVE: Evaluate whether stimulant medication improves acquisition of academic material in children with attention deficit hyperactivity disorder (ADHD) receiving small-group, content-area instruction in a classroom setting.
METHOD: Participants were 173 children between the ages of 7 and 12 years old (77% male, 86% Hispanic) who met Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria for ADHD and were participating in a therapeutic summer camp. The design was a triple-masked, within-subject, AB/BA crossover trial. Children completed two consecutive phases of daily, 25-min instruction in both (a) subject-area content (science, social studies) and (b) vocabulary. Each phase was a standard instructional unit lasting for 3 weeks. Teachers and aides taught the material to small groups in a summer classroom setting. Each child was randomized to be medicated with daily osmotic-release oral system methylphenidate (OROS-MPH) during either the first or second of the instructional phases, receiving placebo during the other.
RESULTS: Medication had large, salutary, statistically significant effects on children's academic seatwork productivity and classroom behavior on every single day of the instructional period. However, there was no detectable effect of medication on learning the material taught during instruction: Children learned the same amount of subject-area and vocabulary content whether they were taking OROS-MPH or placebo during the instructional period.
CONCLUSIONS: Acute effects of OROS-MPH on daily academic seatwork productivity and classroom behavior did not translate into improved learning of new academic material taught via small-group, evidence-based instruction. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

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Year:  2022        PMID: 35604744      PMCID: PMC9443328          DOI: 10.1037/ccp0000725

Source DB:  PubMed          Journal:  J Consult Clin Psychol        ISSN: 0022-006X


  44 in total

1.  The importance of ADHD subtype classification for educational applications of DSM-V.

Authors:  Lucy Barnard; Tara Stevens; Yen M To; William Y Lan; Miriam Mulsow
Journal:  J Atten Disord       Date:  2009-04-16       Impact factor: 3.256

Review 2.  Do stimulant drugs improve the academic performance of hyperkinetic children? A review of outcome studies.

Authors:  R A Barkley; C E Cunningham
Journal:  Clin Pediatr (Phila)       Date:  1978-01       Impact factor: 1.168

3.  Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of Attention-Deficit/Hyperactivity Disorder in Children and Adolescents.

Authors:  Mark L Wolraich; Joseph F Hagan; Carla Allan; Eugenia Chan; Dale Davison; Marian Earls; Steven W Evans; Susan K Flinn; Tanya Froehlich; Jennifer Frost; Joseph R Holbrook; Christoph Ulrich Lehmann; Herschel Robert Lessin; Kymika Okechukwu; Karen L Pierce; Jonathan D Winner; William Zurhellen
Journal:  Pediatrics       Date:  2019-10       Impact factor: 7.124

4.  Comparing treatments for children with ADHD and word reading difficulties: A randomized clinical trial.

Authors:  Leanne Tamm; Carolyn A Denton; Jeffery N Epstein; Christopher Schatschneider; Heather Taylor; L Eugene Arnold; Oscar Bukstein; Julia Anixt; Anson Koshy; Nicholas C Newman; Jan Maltinsky; Patricia Brinson; Richard E A Loren; Mary R Prasad; Linda Ewing-Cobbs; Aaron Vaughn
Journal:  J Consult Clin Psychol       Date:  2017-03-23

5.  Acquiring Science and Social Studies Knowledge in Kindergarten Through Fourth Grade: Conceptualization, Design, Implementation, and Efficacy Testing of Content-Area Literacy Instruction (CALI).

Authors:  Jennifer Dombek; Elizabeth C Crowe; Mercedes Spencer; Elizabeth L Tighe; Sean Coffinger; Elham Zargar; Taffeta Wood; Yaacov Petscher
Journal:  J Educ Psychol       Date:  2016-09-12

6.  How do stimulant treatments for ADHD work? Evidence for mediation by improved cognition.

Authors:  Larry W Hawk; Whitney D Fosco; Craig R Colder; James G Waxmonsky; William E Pelham; Keri S Rosch
Journal:  J Child Psychol Psychiatry       Date:  2018-05-07       Impact factor: 8.982

7.  Last night's sleep in relation to academic achievement and neurocognitive testing performance in adolescents with and without ADHD.

Authors:  Caroline N Cusick; Paul A Isaacson; Joshua M Langberg; Stephen P Becker
Journal:  Sleep Med       Date:  2018-08-21       Impact factor: 3.492

8.  Improving homework performance among children with ADHD: A randomized clinical trial.

Authors:  Brittany M Merrill; Anne S Morrow; Amy R Altszuler; Fiona L Macphee; Elizabeth M Gnagy; Andrew R Greiner; Erika K Coles; Joseph S Raiker; Stefany Coxe; William E Pelham
Journal:  J Consult Clin Psychol       Date:  2016-09-12

9.  The MTA at 8 years: prospective follow-up of children treated for combined-type ADHD in a multisite study.

Authors:  Brooke S G Molina; Stephen P Hinshaw; James M Swanson; L Eugene Arnold; Benedetto Vitiello; Peter S Jensen; Jeffery N Epstein; Betsy Hoza; Lily Hechtman; Howard B Abikoff; Glen R Elliott; Laurence L Greenhill; Jeffrey H Newcorn; Karen C Wells; Timothy Wigal; Robert D Gibbons; Kwan Hur; Patricia R Houck
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2009-05       Impact factor: 8.829

10.  Does methylphenidate improve academic performance? A systematic review and meta-analysis.

Authors:  Anne Fleur Kortekaas-Rijlaarsdam; Marjolein Luman; Edmund Sonuga-Barke; Jaap Oosterlaan
Journal:  Eur Child Adolesc Psychiatry       Date:  2018-01-20       Impact factor: 5.349

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