| Literature DB >> 356045 |
Abstract
ATP induces a conformational change in the Escherichia coli K-12 restriction enzyme that allows it to discriminate between unmodified and modified DNA recognition sequences. This conformational change does not require ATP hydrolysis. However, ATP hydrolysis is a requirement for DNA cleavage.Entities:
Mesh:
Substances:
Year: 1978 PMID: 356045 PMCID: PMC392721 DOI: 10.1073/pnas.75.7.3099
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205