| Literature DB >> 3560401 |
R R Martin, G R Lisehora, M Braxton, P J Barcia.
Abstract
An overdose of a common over-the-counter sodium phosphate enema solution was fatal in an infant. The marked hypernatremia, acidemia, hyperphosphatemia, and hypocalcemia observed before death were also produced in a porcine model. A study using pigs showed that the enema solution was lethal if retained in doses above 20 mL/kg, equivalent to four pediatric-sized enemas in a 2-year-old child. Even normal doses of the enema solution caused measurable changes in serum phosphorus and calcium levels.Entities:
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Year: 1987 PMID： 3560401
Source DB: PubMed Journal: JAMA ISSN： 0098-7484 Impact factor: 56.272