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Literature DB >> 35595818

Transcriptional regulation of the immune checkpoints PD-1 and CTLA-4.

Jing Guo^1,2, Zhonghui Xue^1,3, Lie Wang^4,5.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 2022 PMID： 35595818 PMCID： PMC9243098 DOI： 10.1038/s41423-022-00877-y

Source DB: PubMed Journal: Cell Mol Immunol ISSN： 1672-7681 Impact factor: 22.096

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References

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12 in total

1. NFATc1 regulates PD-1 expression upon T cell activation.

Authors: Kenneth J Oestreich; Hyesuk Yoon; Rafi Ahmed; Jeremy M Boss
Journal: J Immunol Date: 2008-10-01 Impact factor: 5.422

Review 2. Transcriptional and epigenetic regulation of PD-1 expression.

Authors: Zengde Chi; Yan Lu; Yinlong Yang; Bingqing Li; Peiyuan Lu
Journal: Cell Mol Life Sci Date: 2021-03-18 Impact factor: 9.261

3. STAT3, STAT4, NFATc1, and CTCF regulate PD-1 through multiple novel regulatory regions in murine T cells.

Authors: James W Austin; Peiyuan Lu; Parimal Majumder; Rafi Ahmed; Jeremy M Boss
Journal: J Immunol Date: 2014-04-07 Impact factor: 5.422

4. The transcription factor Zfp281 sustains CD4⁺ T lymphocyte activation through directly repressing Ctla-4 transcription.

Authors: Jing Guo; Zhonghui Xue; Ruoyu Ma; Weiwei Yi; Zhaoyuan Hui; Yixin Guo; Yuxi Yao; Wenqiang Cao; Jianli Wang; Zhenyu Ju; Linrong Lu; Lie Wang
Journal: Cell Mol Immunol Date: 2019-09-11 Impact factor: 11.530

10. Blimp-1 represses CD8 T cell expression of PD-1 using a feed-forward transcriptional circuit during acute viral infection.

Authors: Peiyuan Lu; Benjamin A Youngblood; James W Austin; Ata Ur Rasheed Mohammed; Royce Butler; Rafi Ahmed; Jeremy M Boss
Journal: J Exp Med Date: 2014-03-03 Impact factor: 14.307

Transcriptional regulation of the immune checkpoints PD-1 and CTLA-4.

1. NFATc1 regulates PD-1 expression upon T cell activation.

Review 2. Transcriptional and epigenetic regulation of PD-1 expression.

3. STAT3, STAT4, NFATc1, and CTCF regulate PD-1 through multiple novel regulatory regions in murine T cells.

4. The transcription factor Zfp281 sustains CD4⁺ T lymphocyte activation through directly repressing Ctla-4 transcription.

Review 5. The evolutionary legacy of immune checkpoint inhibitors.

6. Notch signaling regulates PD-1 expression during CD8(+) T-cell activation.

7. Activator protein 1 suppresses antitumor T-cell function via the induction of programmed death 1.

8. Impaired proteasome function activates GATA3 in T cells and upregulates CTLA-4: relevance for Sézary syndrome.

Review 9. Regulatory mechanisms of immune checkpoints PD-L1 and CTLA-4 in cancer.

10. Blimp-1 represses CD8 T cell expression of PD-1 using a feed-forward transcriptional circuit during acute viral infection.