| Literature DB >> 35592440 |
Huiqin Lin1, Yuting Wu1, Jinying Wu2, Qiang Chen3, Jun Yu4, Yongjun Lin5.
Abstract
Objective: This study aims to analyze the prevalence of hypertension and 10-year cardiovascular disease (CVD) risk among older adults living in a coastal region of southeast China.Entities:
Keywords: CVD risk; hypertension; older adults; prediction; prevalence
Year: 2022 PMID: 35592440 PMCID: PMC9113549 DOI: 10.2147/RMHP.S341148
Source DB: PubMed Journal: Risk Manag Healthc Policy ISSN: 1179-1594
Socio-Demographic and Clinical Characteristics of the Older Adults in Quanzhou Who Participated in the Study
| Characteristic | All Participants (n = 2018) | Males (n = 986) | Females (n = 1032) | |
|---|---|---|---|---|
| Age (years) | 69.65 ± 15.51 | 69.23 ± 16.46 | 70.11 ± 15.97 | 0.223 |
| Smoking status | <0.001 | |||
| Smoker | 668 (33.1%) | 653 (66.2%) | 15 (1.5%) | |
| Nonsmoker | 1350 (66.9%) | 333 (33.8%) | 1017 (98.5%) | |
| Alcohol consumption | <0.001 | |||
| Regular drinker | 588 (29.1%) | 413 (41.9%) | 175 (17.0%) | |
| Nondrinker/occasional drinker | 1430 (70.9%) | 573 (58.1%) | 857 (83.0%) | |
| Educational level | <0.001 | |||
| Below primary school | 808 (40.0%) | 345 (35.0%) | 463 (44.9%) | |
| Primary school | 546 (27.1%) | 257 (26.1%) | 289 (28.0%) | |
| Junior school | 432 (21.4%) | 245 (24.8%) | 187 (18.1%) | |
| Senior school or above | 232 (11.5%) | 139 (14.1%) | 93 (9.0%) | |
| Physical activity | <0.001 | |||
| Yes | 945 (46.8%) | 598 (60.6%) | 347 (33.6%) | |
| No | 1073 (53.2%) | 388 (39.4%) | 685 (66.4%) | |
| Salt awareness | 0.026 | |||
| Yes | 490 (24.3%) | 218 (22.1%) | 272 (26.4%) | |
| No | 1528 (75.7%) | 768 (77.9%) | 760 (73.6%) | |
| BMI, (kg/m2) | 23.78 ± 4.25 | 24.56 ± 4.12 | 23.11 ± 4.32 | <0.001 |
| Waist circumference (cm) | 82.21 ± 10.41 | 84.54 ± 11.23 | 79.67 ± 10.36 | <0.001 |
| Fasting blood glucose (mmol/L) | 5.42 ± 1.25 | 5.44 ± 1.31 | 5.43 ± 1.26 | 0.861 |
| Total cholesterol (mmol/L) | 5.12 ± 1.18 | 5.13 ± 1.22 | 5.11 ± 1.14 | 0.352 |
| Low-density lipoprotein cholesterol (mmol/L) | 3.37 ± 0.81 | 3.42 ± 0.89 | 3.31 ± 0.76 | 0.003 |
| High-density lipoprotein cholesterol (mmol/L) | 1.03 ± 0.27 | 1.02 ± 0.21 | 1.03 ± 0.32 | 0.204 |
| Triglycerides mmol/L | 1.65 ± 0.76 | 1.62 ± 0.55 | 1.68 ± 0.84 | 0.030 |
| Systolic blood pressure (mmHg) | 134.45 ± 17.32 | 135.76 ± 18.44 | 133.11 ± 17.56 | <0.001 |
| Diastolic blood pressure (mmHg) | 85.11 ± 14.17 | 86.34 ± 15.45 | 83.87 ± 13.69 | <0.001 |
Note: Data are presented as mean ± standard deviation or n (%).
Abbreviation: BMI, body mass index.
Socio-Demographic and Clinical Characteristics of Older Adults in Quanzhou Stratified According to Blood Pressure
| All Participants (n = 2018) | Normotensive (n = 1055) | Prehypertensive (n = 377) | Hypertensive (n = 586) | ||
|---|---|---|---|---|---|
| Age (years) | <0.001 | ||||
| 60–65 | 355 (17.6%) | 177 (16.8%) | 89 (23.6%)a | 89 (15.2%)bc | |
| 66–70 | 596 (29.5%) | 353 (33.5%) | 107 (28.4%) | 136 (23.2%) | |
| 71–75 | 655 (32.5%) | 365 (34.6%) | 96 (25.5%) | 194 (33.1%) | |
| 76–80 | 338 (16.7%) | 127 (12.0%) | 60 (15.9%) | 151 (25.8%) | |
| >80 | 74 (3.7%) | 33 (3.1%) | 25 (6.6%) | 16 (2.7%) | |
| Gender | 0.001 | ||||
| Male | 986 (48.9%) | 473 (44.8%) | 202 (53.6%)a | 311 (53.1%)b | |
| Female | 1032 (51.1%) | 582 (55.2%) | 175 (46.4%) | 275 (46.9%) | |
| Smoking status | <0.001 | ||||
| Smoker | 668 (33.1%) | 107 (10.1%) | 209 (55.4%)a | 352 (60.0%)b | |
| Nonsmoker | 1350 (66.9%) | 948 (89.9%) | 168 (44.6%) | 234 (40.0%) | |
| Alcohol consumption | <0.001 | ||||
| Regular drinker | 588 (29.1%) | 187 (17.7%) | 211 (56.0%)a | 190 (32.4%)bc | |
| Nondrinker/occasional drinker | 1430 (70.9%) | 868 (82.3%) | 166 (44.0%) | 396 (67.6%) | |
| Educational level | 0.703 | ||||
| Below primary school | 808 (40.0%) | 431 (40.9%) | 166 (44.0%) | 211 (36.0%)bc | |
| Primary school | 546 (27.1%) | 287 (27.2%) | 90 (23.9%) | 169 (28.8%) | |
| Junior school | 432 (21.4%) | 183 (17.3%) | 74 (19.6%) | 175 (29.9%) | |
| Senior school or above | 232 (11.5%) | 154 (14.6%) | 47 (12.5%) | 31 (5.3%) | |
| Diabetes mellitus | <0.001 | ||||
| Yes | 456 (22.6%) | 113 (10.7%) | 132 (35.0%)a | 211 (36.0%)b | |
| No | 1562 (77.4%) | 942 (89.3%) | 245 (65.0%) | 375 (64.0%) | |
| Dyslipidemia | <0.001 | ||||
| Yes | 579 (28.7%) | 94 (8.9%) | 189 (50.1%)a | 296 (50.5%)b | |
| No | 1439 (71.3%) | 961 (91.1%) | 188 (49.9%) | 290 (49.5%) | |
| Hyperuricemia | <0.001 | ||||
| Yes | 367 (18.2%) | 106 (10.0%) | 103 (27.3%)a | 158 (27.0%)b | |
| No | 1651 (81.8%) | 949 (90.0%) | 274 (72.7%) | 428 (73.0%) | |
| Body mass index | <0.001 | ||||
| Underweight | 278 (13.8%) | 177 (16.8%) | 50 (13.3%)a | 51 (8.7%)bc | |
| Normal weight | 875 (43.4%) | 588 (55.7%) | 164 (43.5%) | 123 (21.0%) | |
| Overweight | 447 (22.2%) | 132 (12.5%) | 138 (36.6%) | 177 (30.2%) | |
| Obese | 418 (20.7%) | 158 (15.0%) | 25 (6.6%) | 235 (40.1%) | |
| Abdominal obesity | <0.001 | ||||
| Yes | 539 (26.7%) | 167 (15.8%) | 28 (7.4%)a | 344 (58.7%)bc | |
| No | 1479 (73.3%) | 888 (84.2%) | 349 (92.6%) | 242 (41.3%) | |
| Physical activity | <0.001 | ||||
| Yes | 897 (44.4%) | 513 (48.6%) | 240 (63.7%)a | 144 (24.6%)bc | |
| No | 1121 (55.6%) | 542 (51.4%) | 137 (36.3%) | 442 (75.4%) | |
| Salt awareness | <0.001 | ||||
| Yes | 490 (24.3%) | 201 (19.1%) | 125 (33.2%)a | 164 (28.0%)b | |
| No | 1528 (75.7%) | 854 (80.9%) | 252 (66.8%) | 422 (72.0%) |
Notes: Data are presented as n (%). aNormotensive vs prehypertensive, P<0.05; bNormotensive vs hypertensive, P<0.05; cPrehypertensive vs hypertensive, P<0.05.
Multifactor Logistic Analysis of the Effect of Blood Pressure Control in Older Adults Residing in Quanzhou with Hypertension
| Dependent Variable | Factor | B | SE | Wald | Odds Ratio | 95% CI | |
|---|---|---|---|---|---|---|---|
| Prehypertensive | Age, year | 0.809 | 0.287 | 7.911 | 0.009 | 2.248 | 1.136–4.135 |
| Salt awareness (No ref) | 0.435 | 0.204 | 4.542 | 0.042 | 1.337 | 1.122–3.934 | |
| Physical activity (No ref) | 0.872 | 0.385 | 5.259 | 0.034 | 3.334 | 1.215–7.754 | |
| Hypertensive | Age, year | 0.722 | 0.279 | 6.697 | 0.021 | 2.059 | 1.186–4.094 |
| Salt awareness (No ref) | 0.653 | 0.301 | 4.706 | 0.033 | 1.921 | 1.135–3.885 | |
| Physical activity (No ref) | 0.611 | 0.332 | 3.387 | 0.041 | 1.842 | 1.122–3.779 |
Abbreviations: 95% CI, 95% confidence interval; B, coefficient for the constant; SE, standard error of the coefficient for the constant; Wald X2, Wald chi-square statistic.
Associated CVD Risk in Older Adults in Quanzhou
| Low Risk (n = 1002) | Moderate Risk (n = 743) | High Risk (n = 273) | ||
|---|---|---|---|---|
| Gender | <0.003 | |||
| Male | 463 (46.2%) | 365 (49.1%) | 158 (57.9%)bc | |
| Female | 539 (53.8%) | 378 (50.9%) | 115 (42.1%) | |
| Age (years) | 0.009 | |||
| 60–65 | 170 (17.0%) | 108 (14.5%)a | 77 (28.2%)bc | |
| 66–70 | 355 (35.4%) | 172 (23.1%) | 69 (25.3%) | |
| 71–75 | 311 (31.0%) | 284 (38.2%) | 60 (22.0%) | |
| 76–80 | 136 (13.6%) | 153 (20.6%) | 49 (17.9%) | |
| >80 | 30 (3.0%) | 26 (3.5%) | 18 (6.6%) | |
| Blood pressure | <0.001 | |||
| Normotension | 708 (70.6%) | 337 (45.3%)a | 10 (3.7%)bc | |
| Prehypertension | 148 (14.8%) | 187 (25.2%) | 42 (15.4%) | |
| Hypertension | 146 (14.6%) | 219 (29.5%) | 221 (80.9%) |
Notes: aLow risk vs moderate risk, P<0.05; bLow risk vs high risk, P<0.05; cModerate risk vs high risk, P<0.05.