Literature DB >> 35589840

Regulation of wound healing and fibrosis by galectins.

Dong Yu1,2, Ming Bu1,2, Ping Yu1, Yaping Li1,2, Yang Chong3,4.   

Abstract

Galectins are a family of proteins with at least one carbohydrate-recognition domain. Galectins are present in various tissues and organs and participate in different physiological and pathological molecular reactions in vivo. Wound healing is the basic process of traumatic disease recovery. Wound healing involves three overlapping stages: inflammation, proliferation, and remodelling. Furthermore, a comparison of wound healing with the tumour microenvironment revealed that galectin plays a key role in the wound healing process. The current review describes the role of galectin in inflammation, angiogenesis, re-epithelialisation, and fibrous scar formation and evaluates its potential as a therapeutic drug for wounds.
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Angiogenesis; Fibrosis; Galectin; Inflammation; Re-epithelialisation; Wound healing

Mesh：

Substances：

Year:  2022        PMID： 35589840     DOI： 10.1007/s00109-022-02207-1

Source DB:  PubMed          Journal:  J Mol Med (Berl)        ISSN： 0946-2716            Impact factor:   4.599


  110 in total

Review 1.  Introduction to galectins.

Authors:  Hakon Leffler; Susanne Carlsson; Maria Hedlund; Yuning Qian; Francoise Poirier
Journal:  Glycoconj J       Date:  2002       Impact factor: 2.916

2.  Human galectins induce conversion of dermal fibroblasts into myofibroblasts and production of extracellular matrix: potential application in tissue engineering and wound repair.

Authors:  Barbora Dvořánková; Pavol Szabo; Lukas Lacina; Peter Gal; Jana Uhrova; Tomas Zima; Herbert Kaltner; Sabine André; Hans-Joachim Gabius; Eva Sykova; Karel Smetana
Journal:  Cells Tissues Organs       Date:  2011-04-14       Impact factor: 2.481

Review 3.  Role of galectins in re-epithelialization of wounds.

Authors:  Noorjahan Panjwani
Journal:  Ann Transl Med       Date:  2014-09

4.  Microbial glycan microarrays define key features of host-microbial interactions.

Authors:  Sean R Stowell; Connie M Arthur; Ryan McBride; Oren Berger; Nahid Razi; Jamie Heimburg-Molinaro; Lilian C Rodrigues; Jean-Philippe Gourdine; Alexander J Noll; Stephan von Gunten; David F Smith; Yuriy A Knirel; James C Paulson; Richard D Cummings
Journal:  Nat Chem Biol       Date:  2014-05-11       Impact factor: 15.040

Review 5.  The family of metazoan metal-independent beta-galactoside-binding lectins: structure, function and molecular evolution.

Authors:  J Hirabayashi; K Kasai
Journal:  Glycobiology       Date:  1993-08       Impact factor: 4.313

6.  Innate immune lectins kill bacteria expressing blood group antigen.

Authors:  Sean R Stowell; Connie M Arthur; Marcelo Dias-Baruffi; Lilian C Rodrigues; Jean-Philippe Gourdine; Jamie Heimburg-Molinaro; Tongzhong Ju; Ross J Molinaro; Carlos Rivera-Marrero; Baoyun Xia; David F Smith; Richard D Cummings
Journal:  Nat Med       Date:  2010-02-14       Impact factor: 53.440

7.  Apoptosis of T cells mediated by galectin-1.

Authors:  N L Perillo; K E Pace; J J Seilhamer; L G Baum
Journal:  Nature       Date:  1995-12-14       Impact factor: 49.962

Review 8.  Galectin-3 regulation of wound healing and fibrotic processes: insights for chronic skin wound therapeutics.

Authors:  Karrington McLeod; John T Walker; Douglas W Hamilton
Journal:  J Cell Commun Signal       Date:  2018-01-25       Impact factor: 5.782

Review 9.  Galectins: structure, function and therapeutic potential.

Authors:  Ri-Yao Yang; Gabriel A Rabinovich; Fu-Tong Liu
Journal:  Expert Rev Mol Med       Date:  2008-06-13       Impact factor: 5.600

Review 10.  The Role of Galectins as Modulators of Metabolism and Inflammation.

Authors:  Monica Fengsrud Brinchmann; Deepti Manjari Patel; Martin Haugmo Iversen
Journal:  Mediators Inflamm       Date:  2018-05-21       Impact factor: 4.711
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