Literature DB >> 35589250

Therapeutic advances in alcohol-associated hepatitis.

Gyongyi Szabo1, Mark Thursz2, Vijay H Shah3.   

Abstract

In recent years, there have been important advances in our understanding of alcohol-associated hepatitis (AH), which have occurred in parallel with a surge in clinical trial activity. Meanwhile, the broader medical field has seen a transformation in care paradigms based on emerging digital technologies. This review focuses on breakthroughs in our understanding of AH and how these breakthroughs are leading to new paradigms for biomarker discovery, clinical trial activity, and care models for patients. It portends a future in which multimodal data from genetic, radiomic, histologic, and environmental sources can be integrated and synthesised to generate personalised biomarkers and therapies for patients with AH.
Copyright © 2022 European Association for the Study of the Liver. All rights reserved.

Entities:  

Keywords:  Microbiome; Systemic inflammatory response syndrome; Trial design

Mesh:

Substances:

Year:  2022        PMID: 35589250     DOI: 10.1016/j.jhep.2022.03.025

Source DB:  PubMed          Journal:  J Hepatol        ISSN: 0168-8278            Impact factor:   25.083


  3 in total

1.  Advancing proteomics and machine learning in the clinic: an editorial on "Noninvasive proteomic biomarkers for alcohol-related liver disease".

Authors:  Courtney D McGinnis; Brenton I M Graham; Peter S Harris; Kristofer S Fritz
Journal:  Hepatobiliary Surg Nutr       Date:  2022-10       Impact factor: 8.265

Review 2.  Myeloid cells in alcoholic liver diseases: Mechanism and prospect.

Authors:  Wentao Xu; Miaomiao Wu; Bangjie Chen; Hua Wang
Journal:  Front Immunol       Date:  2022-08-10       Impact factor: 8.786

3.  Jia-ga-song-tang protection against alcoholic liver and intestinal damage.

Authors:  Jiamin Fang; Yuhuan Wu; Changlian Gan; Shufang Ruan; Xiaoliang He; Bixia Wang; Ying Wang; Jingtao Yu; Chuanlan Sang; Dawa Zeren; Tianqin Xiong
Journal:  Front Pharmacol       Date:  2022-09-26       Impact factor: 5.988

  3 in total

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