A survivor woman after three years of a cardiac tamponade.

Primary pericardial mesothelioma is an extremely rare tumor, of unclear etiology, nonspecific presentation, with a delay in diagnosis, and a poor prognosis. We present the case of a woman with pericardial mesothelioma, whose main manifestation was cardiac tamponade, currently alive three years after diagnosis and undergoing chemotherapy treatment. <Learning objective: Cardiac tamponade can be the first clinical manifestation of a neoplastic disease, including pericardial mesothelioma, so an adequate diagnostic approach should always be carried out in patients with this clinical picture. Advances in the treatment of pulmonary mesotheliomas have allowed chemotherapy regimens to be adjusted to the treatment of pericardial mesotheliomas, which can increase survival in patients with this type of cancer, which is still considered to have a poor prognosis.>.