Literature DB >> 35576406

Gene Therapy and the Use of Animal Models: Why Mice Alone Are Not Sufficient.

Alisha M Gruntman1,2,3, Terence R Flotte1,2.   

Abstract

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Year:  2022        PMID: 35576406      PMCID: PMC9142770          DOI: 10.1089/hum.2022.29210.amg

Source DB:  PubMed          Journal:  Hum Gene Ther        ISSN: 1043-0342            Impact factor:   4.793


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  4 in total

1.  Intra-Articular Adeno-Associated Virus-Mediated Proteoglycan 4 Gene Therapy for Preventing Posttraumatic Osteoarthritis.

Authors:  Dongrim Seol; Hyeong Hun Choe; Hongjun Zheng; Marc J Brouillette; Douglas C Fredericks; Emily B Petersen; Ino Song; Leela R J Chakka; Aliasger K Salem; James A Martin
Journal:  Hum Gene Ther       Date:  2022-01-07       Impact factor: 4.793

2.  Minimum Effective Dose to Achieve Biochemical Correction with Adeno-Associated Virus Vector-Mediated Gene Therapy in Mice with Pompe Disease.

Authors:  Sang-Oh Han; Dorothy Gheorghiu; Songtao Li; Hye Ri Kang; Dwight Koeberl
Journal:  Hum Gene Ther       Date:  2022-04-27       Impact factor: 5.695

3.  Efficacy and Safety of FX201, a Novel Intra-Articular IL-1Ra Gene Therapy for Osteoarthritis Treatment, in a Rat Model.

Authors:  Rebecca Senter; Rogely Boyce; Marko Repic; Emily Walsh Martin; Monika Chabicovsky; Geneviève Langevin-Carpentier; Agathe Bédard; Neil Bodick
Journal:  Hum Gene Ther       Date:  2022-03-18       Impact factor: 4.793

4.  Efficacy and Safety of a Krabbe Disease Gene Therapy.

Authors:  Juliette Hordeaux; Brianne A Jeffrey; Jinlong Jian; Gourav R Choudhury; Kristofer Michalson; Thomas W Mitchell; Elizabeth L Buza; Jessica Chichester; Cecilia Dyer; Jessica Bagel; Charles H Vite; Allison M Bradbury; James M Wilson
Journal:  Hum Gene Ther       Date:  2022-03-22       Impact factor: 4.793

  4 in total

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