Literature DB >> 35576118

Advances in relationship between cell senescence and atherosclerosis.

Dekun Liu1, Jiali Liu1, Dan Zhang2, Wenqing Yang3.   

Abstract

Cellular senescence is a biological process associated with the degeneration of cell structure and function, which contribute to age-related diseases. Atherosclerosis is a chronic inflammatory disease that can cause a variety of cardiovascular disorders. In this article, we review the effects of cellular senescence on the development of atherosclerosis through diverse physiopathological changes, focusing on the alterations in senescent organelles and the increased senescence-associated secretory phenotype (SASP), and exploring the relevant therapeutic strategies for atherosclerosis by clearing senescent cells and reducing SASP, to provide new insights for the treatment of atherosclerosis.

Entities:  

Keywords:  Atherosclerosis; Organelles; Review; Senescence cells; Senescence-associated secretory phenotype; Treatment strategies

Mesh：

Year:  2022        PMID： 35576118      PMCID： PMC9109755          DOI： 10.3724/zdxbyxb-2021-0270

Source DB:  PubMed          Journal:  Zhejiang Da Xue Xue Bao Yi Xue Ban        ISSN： 1008-9292


  49 in total

1.  Prelamin A accumulation in endothelial cells induces premature senescence and functional impairment.

Authors:  Nathalie Bonello-Palot; Stéphanie Simoncini; Stéphane Robert; Patrice Bourgeois; Florence Sabatier; Nicolas Levy; Françoise Dignat-George; Catherine Badens
Journal:  Atherosclerosis       Date:  2014-08-28       Impact factor: 5.162

2.  Platelet-Derived NO in Subjects Affected by Type 2 Diabetes with and without Complications: Is there any Relationship with their Offspring?

Authors:  Jacopo Sabbatinelli; Arianna Vignini; Eleonora Salvolini; Laura Nanetti; Laura Mazzanti; Rosa Anna Rabini
Journal:  Exp Clin Endocrinol Diabetes       Date:  2017-03-23       Impact factor: 2.949

Review 3.  Vascular Smooth Muscle Cells in Atherosclerosis.

Authors:  Martin R Bennett; Sanjay Sinha; Gary K Owens
Journal:  Circ Res       Date:  2016-02-19       Impact factor: 17.367

4.  Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity.

Authors:  Yuchen Chien; Claudio Scuoppo; Xiaowo Wang; Xueping Fang; Brian Balgley; Jessica E Bolden; Prem Premsrirut; Weijun Luo; Agustin Chicas; Cheng S Lee; Scott C Kogan; Scott W Lowe
Journal:  Genes Dev       Date:  2011-10-06       Impact factor: 11.361

5.  Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis.

Authors:  Tohru Minamino; Toshihiko Yoshida; Kaoru Tateno; Hideyuki Miyauchi; Yonzeng Zou; Haruhiro Toko; Issei Komuro
Journal:  Circulation       Date:  2003-10-13       Impact factor: 29.690

Review 6.  The roles of senescence and telomere shortening in cardiovascular disease.

Authors:  Frej Fyhrquist; Outi Saijonmaa; Timo Strandberg
Journal:  Nat Rev Cardiol       Date:  2013-03-12       Impact factor: 32.419

7.  Restoration of lysosomal pH in RPE cells from cultured human and ABCA4(-/-) mice: pharmacologic approaches and functional recovery.

Authors:  Ji Liu; Wennan Lu; David Reigada; Jonathan Nguyen; Alan M Laties; Claire H Mitchell
Journal:  Invest Ophthalmol Vis Sci       Date:  2008-02       Impact factor: 4.799

8.  Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network.

Authors:  Thomas Kuilman; Chrysiis Michaloglou; Liesbeth C W Vredeveld; Sirith Douma; Remco van Doorn; Christophe J Desmet; Lucien A Aarden; Wolter J Mooi; Daniel S Peeper
Journal:  Cell       Date:  2008-06-13       Impact factor: 41.582

Review 9.  Therapeutic potential of polyphenols in cardiovascular diseases: Regulation of mTOR signaling pathway.

Authors:  Ana Sanches-Silva; Lara Testai; Seyed Fazel Nabavi; Maurizio Battino; Kasi Pandima Devi; Silvia Tejada; Antoni Sureda; Suowen Xu; Bahman Yousefi; Maryam Majidinia; Gian Luigi Russo; Thomas Efferth; Seyed Mohammad Nabavi; Mohammad Hossein Farzaei
Journal:  Pharmacol Res       Date:  2020-01-02       Impact factor: 7.658

10.  Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice.

Authors:  Carolyn M Roos; Bin Zhang; Allyson K Palmer; Mikolaj B Ogrodnik; Tamar Pirtskhalava; Nassir M Thalji; Michael Hagler; Diana Jurk; Leslie A Smith; Grace Casaclang-Verzosa; Yi Zhu; Marissa J Schafer; Tamara Tchkonia; James L Kirkland; Jordan D Miller
Journal:  Aging Cell       Date:  2016-08-05       Impact factor: 9.304
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.