Literature DB >> 35575920

HDL and Lipid Metabolism.

Qi Zhang1, Yilang Ke2, Huashan Hong3.   

Abstract

Mediating reverse cholesterol transport (RCT) is the most classic function of HDL. HDL and HDL-C participate in the entire process of RCT, including cholesterol removal from cells, cholesterol transport in circulation, and cholesterol excretion. As cholesterol is a component of lipid rafts and lipid droplets in cells, HDL and RCT can influence cell activity. HDL has also been shown to be related to the metabolism of some other biological lipids, such as S1P and ox-PL. Here we will introduce in detail the molecular mechanism of HDL participation in RCT and its significance.
© 2022. Springer Nature Singapore Pte Ltd.

Entities:  

Keywords:  ABCA1; Bile acid; Lipid droplets; Reverse cholesterol transport; S1P; Transintestinal cholesterol excretion

Mesh:

Substances:

Year:  2022        PMID: 35575920     DOI: 10.1007/978-981-19-1592-5_4

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  114 in total

1.  LXR-induced redistribution of ABCG1 to plasma membrane in macrophages enhances cholesterol mass efflux to HDL.

Authors:  Nan Wang; Mollie Ranalletta; Fumihiko Matsuura; Felix Peng; Alan R Tall
Journal:  Arterioscler Thromb Vasc Biol       Date:  2006-03-23       Impact factor: 8.311

2.  A PEST deletion mutant of ABCA1 shows impaired internalization and defective cholesterol efflux from late endosomes.

Authors:  Wengen Chen; Nan Wang; Alan R Tall
Journal:  J Biol Chem       Date:  2005-06-10       Impact factor: 5.157

Review 3.  HDL and Reverse Cholesterol Transport.

Authors:  Mireille Ouimet; Tessa J Barrett; Edward A Fisher
Journal:  Circ Res       Date:  2019-05-10       Impact factor: 17.367

Review 4.  Endosomal cholesterol traffic: vesicular and non-vesicular mechanisms meet.

Authors:  M Hölttä-Vuori; E Ikonen
Journal:  Biochem Soc Trans       Date:  2006-06       Impact factor: 5.407

5.  Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice.

Authors:  Laurent Yvan-Charvet; Mollie Ranalletta; Nan Wang; Seongah Han; Naoki Terasaka; Rong Li; Carrie Welch; Alan R Tall
Journal:  J Clin Invest       Date:  2007-12       Impact factor: 14.808

Review 6.  HDL cholesterol and protective factors in atherosclerosis.

Authors:  Gerd Assmann; Antonio M Gotto
Journal:  Circulation       Date:  2004-06-15       Impact factor: 29.690

7.  The ABCA1 transporter modulates late endocytic trafficking: insights from the correction of the genetic defect in Tangier disease.

Authors:  Edward B Neufeld; John A Stonik; Stephen J Demosky; Catherine L Knapper; Christian A Combs; Adele Cooney; Marcella Comly; Nancy Dwyer; Joan Blanchette-Mackie; Alan T Remaley; Silvia Santamarina-Fojo; H Bryan Brewer
Journal:  J Biol Chem       Date:  2004-01-27       Impact factor: 5.157

Review 8.  OSBP-Related Protein Family: Mediators of Lipid Transport and Signaling at Membrane Contact Sites.

Authors:  Henriikka Kentala; Marion Weber-Boyvat; Vesa M Olkkonen
Journal:  Int Rev Cell Mol Biol       Date:  2015-11-18       Impact factor: 6.813

9.  ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins.

Authors:  Nan Wang; Debin Lan; Wengen Chen; Fumihiko Matsuura; Alan R Tall
Journal:  Proc Natl Acad Sci U S A       Date:  2004-06-21       Impact factor: 11.205

10.  Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice.

Authors:  Marit Westerterp; Andrew J Murphy; Mi Wang; Tamara A Pagler; Yuliya Vengrenyuk; Mojdeh S Kappus; Darren J Gorman; Prabhakara R Nagareddy; Xuewei Zhu; Sandra Abramowicz; John S Parks; Carrie Welch; Edward A Fisher; Nan Wang; Laurent Yvan-Charvet; Alan R Tall
Journal:  Circ Res       Date:  2013-04-09       Impact factor: 17.367

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