Literature DB >> 35573140

Factors associated with postoperative visual outcome in acute endophthalmitis after cataract surgery-a cross-sectional, analytical study.

Tharini Senthamizh1, Haripriya Aravind2, Tanpreet Pal Singh2.   

Abstract

Purpose: To identify predictors of visual outcome in patients with acute endophthalmitis following cataract surgery.
Methods: This cross-sectional study included consecutive patients with acute endophthalmitis following cataract surgery at our tertiary care center between January 2017 and June 2018. Baseline demographic details, surgical details, and treatment offered were extracted from the medical record, and patients were followed for 3 months after diagnosis and treatment for endophthalmitis. A good outcome was defined as visual acuity of greater than 6/12; a poor outcome, visual acuity of less than 6/60 on 3-month follow-up. The factors associated with these outcomes were analyzed.
Results: A total of 60 patients were included, of whom 32 (53%) had good visual outcome, and 11 (18%) had poor visual outcome. On univariate analysis, factors associated with good outcome were younger age at surgery, male sex, diabetes, absence of hypopyon, and absence of fibrillary membrane over the intraocular lens (IOL). Poor visual acuity at presentation, inability to visualize the optic disc on indirect ophthalmoscopy, and negative microbiological culture were associated with poor visual outcome. Stepwise logistic regression analysis showed that absent hypopyon (OR = 19.50; 95% CI, 2.87-132.14) and absent fibrillary membrane over the IOL (OR =15.0; 95% CI, 2.34-96.89) were independent factors for good visual outcome. Negative microbiological culture (OR = 18.67; 95% CI, 2.32-150.13) was the only independent factor associated with poor visual outcome. Conclusions: The clinical findings at presentation and microbiological profile play an important role in determining the outcome in patients with acute post-cataract surgery endophthalmitis.
Copyright ©2022. All rights reserved. Reproduction in whole or in part in any form or medium without expressed written permission of the Digital Journal of Ophthalmology is prohibited.

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Year:  2022        PMID: 35573140      PMCID: PMC9070685          DOI: 10.5693/djo.01.2021.08.001

Source DB:  PubMed          Journal:  Digit J Ophthalmol        ISSN: 1542-8958


  20 in total

1.  Microbiologic spectrum and susceptibility of isolates: part I. Postoperative endophthalmitis. Endophthalmitis Research Group.

Authors:  D Y Kunimoto; T Das; S Sharma; S Jalali; A B Majji; U Gopinathan; S Athmanathan; T N Rao
Journal:  Am J Ophthalmol       Date:  1999-08       Impact factor: 5.258

2.  Results in the treatment of postoperative endophthalmitis.

Authors:  J C Olson; H W Flynn; R K Forster; W W Culbertson
Journal:  Ophthalmology       Date:  1983-06       Impact factor: 12.079

3.  Acute endophthalmitis after cataract surgery at a referral centre in Northern Taiwan: review of the causative organisms, antibiotic susceptibility, and clinical features.

Authors:  J-H Cheng; Y-H Chang; C-L Chen; Y-H Chen; D-W Lu; J-T Chen
Journal:  Eye (Lond)       Date:  2010-04-09       Impact factor: 3.775

4.  Recombinant tissue plasminogen activator following paediatric cataract surgery.

Authors:  J S Mehta; G G Adams
Journal:  Br J Ophthalmol       Date:  2000-09       Impact factor: 4.638

5.  Endophthalmitis in the western Sydney region: a case-control study.

Authors:  S Lertsumitkul; P C Myers; M T O'Rourke; J Chandra
Journal:  Clin Exp Ophthalmol       Date:  2001-12       Impact factor: 4.207

6.  Six-year incidence of endophthalmitis after cataract surgery: Swedish national study.

Authors:  Emma Friling; Mats Lundström; Ulf Stenevi; Per Montan
Journal:  J Cataract Refract Surg       Date:  2013-01       Impact factor: 3.351

7.  Acute-onset endophthalmitis after clear corneal cataract surgery (1996-2005). Clinical features, causative organisms, and visual acuity outcomes.

Authors:  Geeta A Lalwani; Harry W Flynn; Ingrid U Scott; Carolyn M Quinn; Audina M Berrocal; Janet L Davis; Timothy G Murray; William E Smiddy; Darlene Miller
Journal:  Ophthalmology       Date:  2007-12-11       Impact factor: 12.079

8.  Polymerase chain reaction identification in aqueous humor of patients with postoperative endophthalmitis.

Authors:  Christophe Chiquet; Gérard Lina; Yvonne Benito; Pierre-Loïc Cornut; Jérôme Etienne; Jean-Paul Romanet; Philippe Denis; François Vandenesch
Journal:  J Cataract Refract Surg       Date:  2007-04       Impact factor: 3.351

9.  Acute-onset postoperative endophthalmitis: review of incidence and visual outcomes (1995-2001).

Authors:  Charles W G Eifrig; Harry W Flynn; Ingrid U Scott; Jean Newton
Journal:  Ophthalmic Surg Lasers       Date:  2002 Sep-Oct

10.  Factors affecting visual outcomes after treatment of infectious endophthalmitis in northeastern Thailand.

Authors:  Yosanan Yospaiboon; Anocha Intarapanich; Wipada Laovirojjanakul; Tanapat Ratanapakorn; Suthasinee Sinawat; Thuss Sanguansak; Chavakij Bhoomibunchoo
Journal:  Clin Ophthalmol       Date:  2018-04-27
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