| Literature DB >> 3555627 |
G J Naylor, A H Smith, P Connelly.
Abstract
Methylene blue, 15 mg/day, was compared with placebo in treatment of severe depressive illness. The 3-week trial was designed to avoid bias by placebo response and also to avoid observer bias. Improvement in patients receiving methylene blue was significantly greater than in those receiving placebo. Methylene blue at a dose of 15 mg/day appears to be a potent antidepressant, and further clinical evaluation is essential.Entities:
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Year: 1987 PMID： 3555627 DOI： 10.1016/0006-3223(87)90194-6
Source DB: PubMed Journal: Biol Psychiatry ISSN： 0006-3223 Impact factor: 13.382