Literature DB >> 3555376

The role of the renin-angiotensin system in normotensive and hypertensive rats with varying renin status.

J Atkinson, N Boillat, A Essadki, P Lüthi, B Maranda, M Sonnay.   

Abstract

We have investigated the relationship between the acute blood pressure lowering effect of captopril and renin status. Differences in renin status were induced by unilateral artery clipping combined with unilateral or bilateral nephrectomy in rats. The blood pressure lowering effect of captopril correlated very closely with plasma or aortic renin across a very wide range of renin levels.

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Year:  1987        PMID: 3555376

Source DB:  PubMed          Journal:  Arch Int Pharmacodyn Ther        ISSN: 0003-9780


  1 in total

1.  The preparation and acute antihypertensive effects of a nanocapsular form of darodipine, a dihydropyridine calcium entry blocker.

Authors:  B Hubert; J Atkinson; M Guerret; M Hoffman; J P Devissaguet; P Maincent
Journal:  Pharm Res       Date:  1991-06       Impact factor: 4.200

  1 in total

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