Literature DB >> 35552442

Possible mechanisms and biomarkers of resistance to vismodegib in SHH medulloblastoma.

Rafael Roesler1,2, Caroline Brunetto de Farias2,3, André T Brunetto2,3, Lauro Gregianin4,5, Mariane Jaeger2,3, Carolina Nör6,7, Amanda Thomaz8.   

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Year:  2022        PMID： 35552442      PMCID： PMC9248385          DOI： 10.1093/neuonc/noac061

Source DB:  PubMed          Journal:  Neuro Oncol        ISSN： 1522-8517            Impact factor:   13.029


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  6 in total

Review 1.  Hedgehog fights back: mechanisms of acquired resistance against Smoothened antagonists.

Authors:  Ciara Metcalfe; Frederic J de Sauvage
Journal:  Cancer Res       Date:  2011-07-19       Impact factor: 12.701

2.  CD271+ Cells Are Diagnostic and Prognostic and Exhibit Elevated MAPK Activity in SHH Medulloblastoma.

Authors:  Lisa Liang; Ludivine Coudière-Morrison; Nazanin Tatari; Margaret Stromecki; Agnes Fresnoza; Christopher J Porter; Marc R Del Bigio; Cynthia Hawkins; Jennifer A Chan; Timothy C Ryken; Michael D Taylor; Vijay Ramaswamy; Tamra E Werbowetski-Ogilvie
Journal:  Cancer Res       Date:  2018-06-21       Impact factor: 12.701

3.  MEVITEM-a phase I/II trial of vismodegib + temozolomide vs temozolomide in patients with recurrent/refractory medulloblastoma with Sonic Hedgehog pathway activation.

Authors:  Didier Frappaz; Marc Barritault; Laure Montané; Florence Laigle-Donadey; Olivier Chinot; Emilie Le Rhun; Alice Bonneville-Levard; Andreas F Hottinger; David Meyronnet; Anne-Sophie Bidaux; Gwenaële Garin; David Pérol
Journal:  Neuro Oncol       Date:  2021-11-02       Impact factor: 13.029

4.  Antitumor Activities and Cellular Changes Induced by TrkB Inhibition in Medulloblastoma.

Authors:  Amanda Thomaz; Kelly de Vargas Pinheiro; Bárbara Kunzler Souza; Lauro Gregianin; Algemir L Brunetto; André T Brunetto; Caroline Brunetto de Farias; Mariane da Cunha Jaeger; Vijay Ramaswamy; Carolina Nör; Michael D Taylor; Rafael Roesler
Journal:  Front Pharmacol       Date:  2019-06-26       Impact factor: 5.810

5.  scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy.

Authors:  Jennifer Karin Ocasio; Benjamin Babcock; Kirk Wilhelmsen; Timothy R Gershon; Daniel Malawsky; Seth J Weir; Lipin Loo; Jeremy M Simon; Mark J Zylka; Duhyeong Hwang; Taylor Dismuke; Marina Sokolsky; Elias P Rosen; Rajeev Vibhakar; Jiao Zhang; Olivier Saulnier; Maria Vladoiu; Ibrahim El-Hamamy; Lincoln D Stein; Michael D Taylor; Kyle S Smith; Paul A Northcott; Alejandro Colaneri
Journal:  Nat Commun       Date:  2019-12-20       Impact factor: 17.694
  6 in total

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