Literature DB >> 35551548

Recipient bed perfusion as a predictor for postoperative complications in irradiated patients with microvascular free tissue transfer of the head and neck area: a clinical analysis of 191 microvascular free flaps.

Yannick Foerster1, Laura Baumann2, Ino Kafantari2, Manuel Olmos2, Falk Wehrhan2, Marco R Kesting2, Raimund Hm Preidl2.   

Abstract

PURPOSE: Despite microvascular free tissue transfer being the mainstay of care in the reconstruction of larger maxillofacial defects, a significant number of patients experience postoperative complications due to impaired blood supply of the flap. In this context, the early influence of recipient bed perfusion remains unclear, but there is evidence that it is associated with free flap viability immediately after surgery.
METHODS: We analyzed flap and recipient bed perfusion within the first 2 weeks after surgery by using the oxygen-to-see device. One hundred ninety-one patients who underwent free flap surgery in our department were included.
RESULTS: Flow parameters were higher and postoperative complications were less frequent in radial forearm free flaps compared to any other type of flap. Flow parameters of the recipient bed were higher than transferred tissue at all times, implicating flap autonomization is not completed within 2 weeks. Previous radiotherapy significantly decreased flow parameters of the recipient bed but not of the flaps. Furthermore, irradiated patients with postoperative complications were found to have reduced flow parameters of their recipient bed compared to non-irradiated patients with postoperative complications.
CONCLUSION: We conclude that monitoring of recipient bed perfusion is useful for detecting flap compromise of irradiated patients in the early postoperative period.
© 2022. The Author(s).

Entities:  

Keywords:  Complications; Microvascular free flap; Monitoring; Oxygen-to-see; Radiotherapy; Recipient bed

Year:  2022        PMID: 35551548     DOI: 10.1007/s10006-022-01070-1

Source DB:  PubMed          Journal:  Oral Maxillofac Surg        ISSN: 1865-1550


  5 in total

1.  Transforming growth factor beta1 and beta2 (TGFbeta2 / TGFbeta2) profile changes in previously irradiated free flap beds.

Authors:  Stefan Schultze-Mosgau; Falk Wehrhan; Gerhard Grabenbauer; Kerstin Amann; Martin Radespiel-Tröger; Friedrich Wilhelm Neukam; Franz Rodel
Journal:  Head Neck       Date:  2002-01       Impact factor: 3.147

2.  Transforming growth factor-beta receptor-II up-regulation during wound healing in previously irradiated graft beds in vivo.

Authors:  Stefan Schultze-Mosgau; Falk Wehrhan; Franz Rödel; Kerstin Amann; Martin Radespiel-Tröger; Gerhard G Grabenbauer
Journal:  Wound Repair Regen       Date:  2003 Jul-Aug       Impact factor: 3.617

3.  Transforming growth factor beta 1 dependent regulation of Tenascin-C in radiation impaired wound healing.

Authors:  Falk Wehrhan; Franz Rödel; Gerhard G Grabenbauer; Kerstin Amann; Wolfgang Brückl; Stefan Schultze-Mosgau
Journal:  Radiother Oncol       Date:  2004-09       Impact factor: 6.280

4.  Exogenous modulation of TGF-beta(1) influences TGF-betaR-III-associated vascularization during wound healing in irradiated tissue.

Authors:  Falk Wehrhan; Gerhard G Grabenbauer; Franz Rödel; Kerstin Amann; Stefan Schultze-Mosgau
Journal:  Strahlenther Onkol       Date:  2004-08       Impact factor: 3.621

5.  A decade of reconstructive surgery: outcome and perspectives of free tissue transfer in the head and neck. Experience of a single center institution.

Authors:  Steffen Spoerl; Shlomo Schoedel; Gerrit Spanier; Karolina Mueller; Johannes K Meier; Torsten E Reichert; Tobias Ettl
Journal:  Oral Maxillofac Surg       Date:  2020-03-20
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.