Literature DB >> 3555126

ECG changes during haloperidol and pimozide treatment of Tourette's disorder.

G Fulop, R A Phillips, A K Shapiro, J A Gomes, E Shapiro, J W Nordlie.   

Abstract

The ECG QTc interval was significantly prolonged by pimozide but not haloperidol or placebo in a randomized clinical trial with 40 patients with Tourette's disorder. However, no adverse cardiac effects or differences in rate, rhythm, or waveform were found.

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Year:  1987        PMID: 3555126     DOI: 10.1176/ajp.144.5.673

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN: 0002-953X            Impact factor:   18.112


  18 in total

Review 1.  Pharmacokinetic factors in the adverse cardiovascular effects of antipsychotic drugs.

Authors:  Candace S Brown; Richard G Farmer; Judith E Soberman; Samantha F Eichner
Journal:  Clin Pharmacokinet       Date:  2004       Impact factor: 6.447

Review 2.  The significance of QT interval in drug development.

Authors:  Rashmi R Shah
Journal:  Br J Clin Pharmacol       Date:  2002-08       Impact factor: 4.335

3.  Cardiovascular safety of aripiprazole and pimozide in young patients with Tourette syndrome.

Authors:  Mariangela Gulisano; Paola V Calì; Andrea E Cavanna; Clare Eddy; Hugh Rickards; Renata Rizzo
Journal:  Neurol Sci       Date:  2011-07-06       Impact factor: 3.307

4.  In-Hospital Haloperidol Use and Perioperative Changes in QTc-Duration.

Authors:  M T Blom; S Jansen; A de Jonghe; B C van Munster; A de Boer; S E de Rooij; H L Tan; N van der Velde
Journal:  J Nutr Health Aging       Date:  2015-05       Impact factor: 4.075

5.  Inhibition by various antipsychotic drugs of the G-protein-activated inwardly rectifying K(+) (GIRK) channels expressed in xenopus oocytes.

Authors:  T Kobayashi; K Ikeda; T Kumanishi
Journal:  Br J Pharmacol       Date:  2000-04       Impact factor: 8.739

Review 6.  Gilles de la Tourette syndrome: symptomatic treatment based on evidence.

Authors:  M M Robertson; J S Stern
Journal:  Eur Child Adolesc Psychiatry       Date:  2000       Impact factor: 4.785

Review 7.  [Lengthening of QT interval by antipsychotic drugs].

Authors:  W Haverkamp; M Deuschle
Journal:  Nervenarzt       Date:  2006-03       Impact factor: 1.214

Review 8.  Antipsychotic-related QTc prolongation, torsade de pointes and sudden death.

Authors:  Peter M Haddad; Ian M Anderson
Journal:  Drugs       Date:  2002       Impact factor: 9.546

Review 9.  Ziprasidone in the management of schizophrenia : the QT interval issue in context.

Authors:  David Taylor
Journal:  CNS Drugs       Date:  2003       Impact factor: 5.749

Review 10.  Pharmacogenetic aspects of drug-induced torsade de pointes: potential tool for improving clinical drug development and prescribing.

Authors:  Rashmi R Shah
Journal:  Drug Saf       Date:  2004       Impact factor: 5.606

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