Literature DB >> 3554809

Recombinant vaccinia virus LC16m0 or LC16m8 that expresses hepatitis B surface antigen while preserving the attenuation of the parental virus strain.

M Morita, K Suzuki, A Yasuda, A Kojima, M Sugimoto, K Watanabe, H Kobayashi, K Kajima, S Hashizume.   

Abstract

Thymidine kinase-negative recombinant vaccinia virus LC16m0 or LC16m8 expressing hepatitis B surface antigen preserved almost the same pathogenicity as their parental thymidine kinase-positive attenuated virus strains. The results demonstrate the potential for using the LC16m0 or LC16m8 virus strain as a vector for recombinant vaccine.

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Year:  1987        PMID： 3554809     DOI： 10.1016/0264-410x(87)90012-0

Source DB:  PubMed          Journal:  Vaccine        ISSN： 0264-410X            Impact factor:   3.641


  7 in total

1.  Partial deletion of the human host range gene in the attenuated vaccinia virus MVA.

Authors:  W Altenburger; C P Süter; J Altenburger
Journal:  Arch Virol       Date:  1989       Impact factor: 2.574

2.  An attenuated LC16m8 smallpox vaccine: analysis of full-genome sequence and induction of immune protection.

Authors:  Shigeru Morikawa; Tokuki Sakiyama; Hideki Hasegawa; Masayuki Saijo; Akihiko Maeda; Ichiro Kurane; Go Maeno; Junko Kimura; Chie Hirama; Teruhiko Yoshida; Yasuko Asahi-Ozaki; Tetsutaro Sata; Takeshi Kurata; Asato Kojima
Journal:  J Virol       Date:  2005-09       Impact factor: 5.103

3.  Molecular attenuation of vaccinia virus: mutant generation and animal characterization.

Authors:  M S Lee; J M Roos; L C McGuigan; K A Smith; N Cormier; L K Cohen; B E Roberts; L G Payne
Journal:  J Virol       Date:  1992-05       Impact factor: 5.103

4.  Induction of protective immunity in animals vaccinated with recombinant vaccinia viruses that express PreM and E glycoproteins of Japanese encephalitis virus.

Authors:  A Yasuda; J Kimura-Kuroda; M Ogimoto; M Miyamoto; T Sata; T Sato; C Takamura; T Kurata; A Kojima; K Yasui
Journal:  J Virol       Date:  1990-06       Impact factor: 5.103

5.  The live vector approach-viruses.

Authors:  M Mackett
Journal:  World J Microbiol Biotechnol       Date:  1991-03       Impact factor: 3.312

6.  Intravenous inoculation of replication-deficient recombinant vaccinia virus DIs expressing simian immunodeficiency virus gag controls highly pathogenic simian-human immunodeficiency virus in monkeys.

Authors:  Yasuyuki Izumi; Yasushi Ami; Kazuhiro Matsuo; Kenji Someya; Tetsutaro Sata; Naoki Yamamoto; Mitsuo Honda
Journal:  J Virol       Date:  2003-12       Impact factor: 5.103

Review 7.  LC16m8: an attenuated smallpox vaccine.

Authors:  Julie Kenner; Fiona Cameron; Cyril Empig; David V Jobes; Marc Gurwith
Journal:  Vaccine       Date:  2006-04-21       Impact factor: 3.641
  7 in total

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