Literature DB >> 35544036

New insights into IRE1α activation and function in anti-tumor immunity.

Susan E Logue1,2, Adrienne M Gorman3,4,5, Afshin Samali3,4,5.   

Abstract

Logue, Gorman, and Samali highlight a study by Guttman and colleagues (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202111068) that shows exogenous antigen peptides imported into the ER can activate the ER stress sensor IRE1α, attenuating cross-presentation by dendritic cells.
© 2022 Logue et al.

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Year:  2022        PMID： 35544036      PMCID： PMC9099116          DOI： 10.1083/jcb.202205019

Source DB:  PubMed          Journal:  J Cell Biol        ISSN： 0021-9525            Impact factor:   8.077


  8 in total

1.  Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response.

Authors:  A Bertolotti; Y Zhang; L M Hendershot; H P Harding; D Ron
Journal:  Nat Cell Biol       Date:  2000-06       Impact factor: 28.824

2.  The unfolded-protein-response sensor IRE-1α regulates the function of CD8α+ dendritic cells.

Authors:  Fabiola Osorio; Simon J Tavernier; Eik Hoffmann; Yvan Saeys; Liesbet Martens; Jessica Vetters; Iris Delrue; Riet De Rycke; Eef Parthoens; Philippe Pouliot; Takao Iwawaki; Sophie Janssens; Bart N Lambrecht
Journal:  Nat Immunol       Date:  2014-01-19       Impact factor: 25.606

3.  Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.

Authors:  Julie Hollien; Jonathan S Weissman
Journal:  Science       Date:  2006-07-07       Impact factor: 47.728

4.  Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival.

Authors:  Simon J Tavernier; Fabiola Osorio; Lana Vandersarren; Jessica Vetters; Nele Vanlangenakker; Gert Van Isterdael; Karl Vergote; Riet De Rycke; Eef Parthoens; Lianne van de Laar; Takao Iwawaki; Juan R Del Valle; Chih-Chi Andrew Hu; Bart N Lambrecht; Sophie Janssens
Journal:  Nat Cell Biol       Date:  2017-05-01       Impact factor: 28.824

5.  Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response.

Authors:  Brooke M Gardner; Peter Walter
Journal:  Science       Date:  2011-08-18       Impact factor: 47.728

6.  Identification of a consensus element recognized and cleaved by IRE1 alpha.

Authors:  Daisuke Oikawa; Mio Tokuda; Akira Hosoda; Takao Iwawaki
Journal:  Nucleic Acids Res       Date:  2010-05-27       Impact factor: 16.971

7.  Antigen-derived peptides engage the ER stress sensor IRE1α to curb dendritic cell cross-presentation.

Authors:  Ofer Guttman; Adrien Le Thomas; Scot Marsters; David A Lawrence; Lauren Gutgesell; Iratxe Zuazo-Gaztelu; Jonathan M Harnoss; Simone M Haag; Aditya Murthy; Geraldine Strasser; Zora Modrusan; Thomas Wu; Ira Mellman; Avi Ashkenazi
Journal:  J Cell Biol       Date:  2022-04-21       Impact factor: 8.077

8.  The transcription factor XBP-1 is essential for the development and survival of dendritic cells.

Authors:  Neal N Iwakoshi; Marc Pypaert; Laurie H Glimcher
Journal:  J Exp Med       Date:  2007-09-17       Impact factor: 14.307
  8 in total

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