Literature DB >> 35534633

Understudied proteins: opportunities and challenges for functional proteomics.

Georg Kustatscher1, Tom Collins2, Anne-Claude Gingras3,4, Tiannan Guo5,6, Henning Hermjakob7, Trey Ideker8, Kathryn S Lilley9, Emma Lundberg10,11,12,13, Edward M Marcotte14, Markus Ralser15,16, Juri Rappsilber17,18.   

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Year:  2022        PMID: 35534633     DOI: 10.1038/s41592-022-01454-x

Source DB:  PubMed          Journal:  Nat Methods        ISSN: 1548-7091            Impact factor:   47.990


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  89 in total

1.  Too many roads not taken.

Authors:  Aled M Edwards; Ruth Isserlin; Gary D Bader; Stephen V Frye; Timothy M Willson; Frank H Yu
Journal:  Nature       Date:  2011-02-10       Impact factor: 49.962

2.  The most popular genes in the human genome.

Authors:  Elie Dolgin
Journal:  Nature       Date:  2017-11-23       Impact factor: 49.962

Review 3.  Unexplored therapeutic opportunities in the human genome.

Authors:  Tudor I Oprea; Cristian G Bologa; Søren Brunak; Allen Campbell; Gregory N Gan; Anna Gaulton; Shawn M Gomez; Rajarshi Guha; Anne Hersey; Jayme Holmes; Ajit Jadhav; Lars Juhl Jensen; Gary L Johnson; Anneli Karlson; Andrew R Leach; Avi Ma'ayan; Anna Malovannaya; Subramani Mani; Stephen L Mathias; Michael T McManus; Terrence F Meehan; Christian von Mering; Daniel Muthas; Dac-Trung Nguyen; John P Overington; George Papadatos; Jun Qin; Christian Reich; Bryan L Roth; Stephan C Schürer; Anton Simeonov; Larry A Sklar; Noel Southall; Susumu Tomita; Ilinca Tudose; Oleg Ursu; Dušica Vidovic; Anna Waller; David Westergaard; Jeremy J Yang; Gergely Zahoránszky-Köhalmi
Journal:  Nat Rev Drug Discov       Date:  2018-03-23       Impact factor: 84.694

4.  Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes.

Authors:  Mark D M Leiserson; Fabio Vandin; Hsin-Ta Wu; Jason R Dobson; Jonathan V Eldridge; Jacob L Thomas; Alexandra Papoutsaki; Younhun Kim; Beifang Niu; Michael McLellan; Michael S Lawrence; Abel Gonzalez-Perez; David Tamborero; Yuwei Cheng; Gregory A Ryslik; Nuria Lopez-Bigas; Gad Getz; Li Ding; Benjamin J Raphael
Journal:  Nat Genet       Date:  2014-12-15       Impact factor: 38.330

5.  Gene annotation bias impedes biomedical research.

Authors:  Winston A Haynes; Aurelie Tomczak; Purvesh Khatri
Journal:  Sci Rep       Date:  2018-01-22       Impact factor: 4.379

6.  Hidden in plain sight: what remains to be discovered in the eukaryotic proteome?

Authors:  Valerie Wood; Antonia Lock; Midori A Harris; Kim Rutherford; Jürg Bähler; Stephen G Oliver
Journal:  Open Biol       Date:  2019-02-28       Impact factor: 6.411

7.  Darkness in the Human Gene and Protein Function Space: Widely Modest or Absent Illumination by the Life Science Literature and the Trend for Fewer Protein Function Discoveries Since 2000.

Authors:  Swati Sinha; Birgit Eisenhaber; Lars Juhl Jensen; Bharata Kalbuaji; Frank Eisenhaber
Journal:  Proteomics       Date:  2018-10-30       Impact factor: 3.984

8.  Human genes: Time to follow the roads less traveled?

Authors:  Ian Dunham
Journal:  PLoS Biol       Date:  2018-09-26       Impact factor: 8.029

9.  Large-scale investigation of the reasons why potentially important genes are ignored.

Authors:  Thomas Stoeger; Martin Gerlach; Richard I Morimoto; Luís A Nunes Amaral
Journal:  PLoS Biol       Date:  2018-09-18       Impact factor: 8.029

10.  Estimating cumulative point prevalence of rare diseases: analysis of the Orphanet database.

Authors:  Stéphanie Nguengang Wakap; Deborah M Lambert; Annie Olry; Charlotte Rodwell; Charlotte Gueydan; Valérie Lanneau; Daniel Murphy; Yann Le Cam; Ana Rath
Journal:  Eur J Hum Genet       Date:  2019-09-16       Impact factor: 4.246

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  5 in total

1.  An open invitation to the Understudied Proteins Initiative.

Authors:  Georg Kustatscher; Tom Collins; Anne-Claude Gingras; Tiannan Guo; Henning Hermjakob; Trey Ideker; Kathryn S Lilley; Emma Lundberg; Edward M Marcotte; Markus Ralser; Juri Rappsilber
Journal:  Nat Biotechnol       Date:  2022-06       Impact factor: 68.164

2.  Molecular Modelling Hurdle in the Next-Generation Sequencing Era.

Authors:  Guerau Fernandez; Dèlia Yubero; Francesc Palau; Judith Armstrong
Journal:  Int J Mol Sci       Date:  2022-06-28       Impact factor: 6.208

Review 3.  Updated List of Transport Proteins in Plasmodium falciparum.

Authors:  Juliane Wunderlich
Journal:  Front Cell Infect Microbiol       Date:  2022-06-24       Impact factor: 6.073

Review 4.  Single-Stranded DNA Binding Proteins and Their Identification Using Machine Learning-Based Approaches.

Authors:  Jun-Tao Guo; Fareeha Malik
Journal:  Biomolecules       Date:  2022-08-26

5.  The dark side of the ribosome life cycle.

Authors:  Sébastien Ferreira-Cerca
Journal:  RNA Biol       Date:  2022-01       Impact factor: 4.766

  5 in total

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