Literature DB >> 3553346

Immunization with glycoprotein subunits of respiratory syncytial virus to protect cotton rats against viral infection.

E E Walsh, C B Hall, M Briselli, M W Brandriss, J J Schlesinger.   

Abstract

The cotton rat model of respiratory syncytial virus infection was used to study immunization with viral glycoproteins. Animals immunized with the purified attachment protein (G) or the fusion protein (F) developed complete pulmonary resistance, but only partial nasal resistance, to challenge with respiratory syncytial virus. Antibody produced to the G protein neutralized virus, whereas antibody to the F protein neutralized virus and also inhibited fusion of infected cells. There was no evidence of enhanced pulmonary pathology in any immunized group.

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Year:  1987        PMID： 3553346     DOI： 10.1093/infdis/155.6.1198

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


  40 in total

1.  Neutralization of human respiratory syncytial virus infectivity by antibodies and low-molecular-weight compounds targeted against the fusion glycoprotein.

Authors:  Margarita Magro; David Andreu; Paulino Gómez-Puertas; José A Melero; Concepción Palomo
Journal:  J Virol       Date:  2010-06-09       Impact factor: 5.103

2.  Premature stop codons in the G glycoprotein of human respiratory syncytial viruses resistant to neutralization by monoclonal antibodies.

Authors:  P Rueda; T Delgado; A Portela; J A Melero; B García-Barreno
Journal:  J Virol       Date:  1991-06       Impact factor: 5.103

3.  Antibody response to the central unglycosylated region of the respiratory syncytial virus attachment protein in mice.

Authors:  Yoshihiko Murata; Seana C Catherman
Journal:  Vaccine       Date:  2012-06-19       Impact factor: 3.641

4.  Respiratory syncytial virus infection in C57BL/6 mice: clearance of virus from the lungs with virus-specific cytotoxic T cells.

Authors:  J L Muñoz; C A McCarthy; M E Clark; C B Hall
Journal:  J Virol       Date:  1991-08       Impact factor: 5.103

5.  Induction of a neutralizing immune response to human respiratory syncytial virus with anti-idiotypic antibodies.

Authors:  C Palomo; J P Albar; B García-Barreno; J A Melero
Journal:  J Virol       Date:  1990-09       Impact factor: 5.103

6.  Role of individual glycoproteins of human parainfluenza virus type 3 in the induction of a protective immune response.

Authors:  R Ray; B J Glaze; R W Compans
Journal:  J Virol       Date:  1988-03       Impact factor: 5.103

Review 7.  Immunity to human and bovine respiratory syncytial virus.

Authors:  T G Kimman; F Westenbrink
Journal:  Arch Virol       Date:  1990       Impact factor: 2.574

8.  Antigenic analysis of the F protein of the bovine respiratory syncytial virus: identification of two distinct antigenic sites involved in fusion inhibition.

Authors:  J P Matheise; K Walravens; A Collard; P Coppe; J J Letesson
Journal:  Arch Virol       Date:  1995       Impact factor: 2.574

Review 9.  Hyperimmune globulins in prevention and treatment of respiratory syncytial virus infections.

Authors:  V G Hemming; G A Prince; J R Groothuis; G R Siber
Journal:  Clin Microbiol Rev       Date:  1995-01       Impact factor: 26.132

10.  Soluble F proteins exacerbate pulmonary histopathology after vaccination upon respiratory syncytial virus challenge but not when presented on virus-like particles.

Authors:  Youri Lee; Young-Tae Lee; Eun-Ju Ko; Ki-Hye Kim; Hye Suk Hwang; Soojin Park; Young-Man Kwon; Sang Moo Kang
Journal:  Hum Vaccin Immunother       Date:  2017-11-02       Impact factor: 3.452
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