Literature DB >> 35529670

Reactive oxygen species explicit dosimetry (ROSED) for fractionated photofrin-mediated photodynamic therapy (PDT).

Hongjing Sun1, Yi Hong Ong1, Timothy C Zhu1.   

Abstract

Photodynamic therapy (PDT) is an established modality for cancer treatment and reactive oxygen species explicit dosimetry (ROSED), based on direct measurements of in-vivo light fluence (rate), in-vivo photofrin concentration, and tissue oxygenation concentration, has been proved to be an effective dosimetric quantity which can be used to predict PDT outcome. In this study, ROSED was performed for photofrin-mediated PDT for mice bearing radiation-induced fibrosacorma (RIF) tumor. PDT treatments were performed using single or fractionated illumination to a same total fluence of 135 Jcm-2. The effects of light fractionation on the total reacted [ROS]rx and treatment outcomes were evaluated.

Entities:  

Keywords:  Photofrin; explicit dosimetry; light fractionation; photodynamic therapy; reactive oxygen species

Year:  2022        PMID： 35529670      PMCID： PMC9075689          DOI： 10.1117/12.2609969

Source DB:  PubMed          Journal:  Proc SPIE Int Soc Opt Eng        ISSN： 0277-786X


  9 in total

1.  Fractionated illumination after topical application of 5-aminolevulinic acid on normal skin of hairless mice: the influence of the dark interval.

Authors:  H S de Bruijn; A van der Ploeg-van den Heuvel; H J C M Sterenborg; D J Robinson
Journal:  J Photochem Photobiol B       Date:  2006-09-01       Impact factor: 6.252

2.  Effect of photosensitizer dose on fluence rate responses to photodynamic therapy.

Authors:  Hsing-Wen Wang; Elizabeth Rickter; Min Yuan; E Paul Wileyto; Eli Glatstein; Arjun Yodh; Theresa M Busch
Journal:  Photochem Photobiol       Date:  2007 Sep-Oct       Impact factor: 3.421

3.  Fluence rate-dependent intratumor heterogeneity in physiologic and cytotoxic responses to Photofrin photodynamic therapy.

Authors:  Theresa M Busch; Xiaoman Xing; Guoqiang Yu; Arjun Yodh; E Paul Wileyto; Hsing-Wen Wang; Turgut Durduran; Timothy C Zhu; Ken Kang-Hsin Wang
Journal:  Photochem Photobiol Sci       Date:  2009-10-15       Impact factor: 3.982

4.  Evaluation of singlet oxygen explicit dosimetry for predicting treatment outcomes of benzoporphyrin derivative monoacid ring A-mediated photodynamic therapy.

Authors:  Michele M Kim; Rozhin Penjweini; Timothy C Zhu
Journal:  J Biomed Opt       Date:  2017-02-01       Impact factor: 3.170

5.  Light fractionation significantly improves the response of superficial basal cell carcinoma to aminolaevulinic acid photodynamic therapy: five-year follow-up of a randomized, prospective trial.

Authors:  Hannah C de Vijlder; Henricus J C M Sterenborg; H A Martino Neumann; Dominic J Robinson; Ellen R M de Haas
Journal:  Acta Derm Venereol       Date:  2012-11       Impact factor: 4.437

6.  PDT dose dosimetry for Photofrin-mediated pleural photodynamic therapy (pPDT).

Authors:  Yi Hong Ong; Michele M Kim; Jarod C Finlay; Andreea Dimofte; Sunil Singhal; Eli Glatstein; Keith A Cengel; Timothy C Zhu
Journal:  Phys Med Biol       Date:  2017-12-29       Impact factor: 3.609

7.  Reactive Oxygen Species Explicit Dosimetry (ROSED) of a Type 1 Photosensitizer.

Authors:  Yi Hong Ong; Michele M Kim; Zheng Huang; Timothy C Zhu
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2018-02

8.  Reactive oxygen species explicit dosimetry to predict tumor growth for benzoporphyrin derivative-mediated vascular photodynamic therapy.

Authors:  Tianqi Sheng; Yi Hong Ong; Wensheng Guo; Timothy Zhu
Journal:  J Biomed Opt       Date:  2020-01       Impact factor: 3.170

9.  Blood Flow Measurements Enable Optimization of Light Delivery for Personalized Photodynamic Therapy.

Authors:  Yi Hong Ong; Joann Miller; Min Yuan; Malavika Chandra; Mirna El Khatib; Sergei A Vinogradov; Mary E Putt; Timothy C Zhu; Keith A Cengel; Arjun G Yodh; Theresa M Busch
Journal:  Cancers (Basel)       Date:  2020-06-15       Impact factor: 6.639
  9 in total

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