Literature DB >> 35528748

Lower Extremity Varicose Veins: An Unusual Presentation of Small Bowel Leiomyosarcoma.

Karim Abou El Joud1, Misha Abbasi1.   

Abstract

Leiomyosarcomas (LMSs) are extremely rare and comprise only 1.2% of small bowel malignancies. Advancements in immunohistochemical techniques have allowed for the differentiation between LMSs and gastrointestinal stromal tumors. LMSs remain difficult to detect via endoscopy and require a more intricate diagnostic approach. The staging and sizing of these tumors are important prognostic indicators. We report a case of a 67-year-old male who presented with bulging lower extremity veins, abdominal bloating, and weight loss. A CT of the abdomen and pelvis revealed a pelvic mass arising from the small bowel and a metastatic hepatic lesion, which was found to be compressing the inferior vena cava. A biopsy of the hepatic lesion confirmed the diagnosis of metastatic LMS.
Copyright © 2021 by S. Karger AG, Basel.

Entities:  

Keywords:  Gastrointestinal stromal tumor; Leiomyosarcoma; Small intestine; Stromal tumors

Year:  2021        PMID: 35528748      PMCID: PMC9021616          DOI: 10.1159/000520802

Source DB:  PubMed          Journal:  Gastrointest Tumors        ISSN: 2296-3774


  14 in total

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Journal:  Surg Clin North Am       Date:  2011-02       Impact factor: 2.741

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4.  Smooth muscle tumors of the gastrointestinal tract. A study of 56 cases followed for a minimum of 10 years.

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Journal:  Cancer       Date:  1985-11-01       Impact factor: 6.860

5.  Conservative surgery and postoperative radiotherapy in 300 adults with soft-tissue sarcomas.

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Journal:  Cancer       Date:  1981-05-15       Impact factor: 6.860

Review 6.  Primary leiomyosarcomas of the gastrointestinal tract in the post-gastrointestinal stromal tumor era.

Authors:  Gitika Aggarwal; Suash Sharma; Mei Zheng; Michelle D Reid; John H Crosby; Sherman M Chamberlain; Asha Nayak-Kapoor; Jeffrey R Lee
Journal:  Ann Diagn Pathol       Date:  2012-08-20       Impact factor: 2.090

7.  Small bowel cancer in the United States: changes in epidemiology, treatment, and survival over the last 20 years.

Authors:  Karl Y Bilimoria; David J Bentrem; Jeffrey D Wayne; Clifford Y Ko; Charles L Bennett; Mark S Talamonti
Journal:  Ann Surg       Date:  2009-01       Impact factor: 12.969

Review 8.  Small bowel adenocarcinomas--existing evidence and evolving paradigms.

Authors:  Kanwal Raghav; Michael J Overman
Journal:  Nat Rev Clin Oncol       Date:  2013-07-30       Impact factor: 66.675

9.  Leiomyosarcoma of the small and large bowel.

Authors:  O E Akwari; R R Dozois; L H Weiland; O H Beahrs
Journal:  Cancer       Date:  1978-09       Impact factor: 6.860

10.  DOG1 is useful for diagnosis of KIT-negative gastrointestinal stromal tumor of stomach.

Authors:  Takuya Wada; Satoshi Tanabe; Kenji Ishido; Katsuhiko Higuchi; Tohru Sasaki; Chikatoshi Katada; Mizutomo Azuma; Akira Naruke; Myunguchul Kim; Wasaburo Koizumi; Tetsuo Mikami
Journal:  World J Gastroenterol       Date:  2013-12-21       Impact factor: 5.742

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