Sepideh Mirzaei1, Mohammad Hossein Gholami2, Kiavash Hushmandi3, Farid Hashemi4, Amirhossein Zabolian5, Israel Canadas6, Ali Zarrabi7, Noushin Nabavi8, Amir Reza Aref9,10, Francesco Crea11, Yuzhuo Wang12, Milad Ashrafizadeh13, Alan Prem Kumar14,15. 1. Department of Biology, Faculty of Science, Islamic Azad University, Science and Research Branch, Tehran, Iran. 2. Faculty of Veterinary Medicine, Kazerun Branch, Islamic Azad University, Kazerun, Iran. 3. Department of Food Hygiene and Quality Control, Division of Epidemiology and Zoonoses, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran. 4. Department of Comparative Biosciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, 1417466191, Iran. 5. Department of Orthopedics, School of Medicine, 5Th Azar Hospital, Golestan University of Medical Sciences, Gorgan, Golestan, Iran. 6. Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, PA, USA. 7. Department of Biomedical Engineering, Faculty of Engineering and Natural Sciences, Istinye University, Istanbul, 34396, Turkey. 8. Department of Urological Sciences and Vancouver Prostate Centre, University of British Columbia, Vancouver, BC, V6H3Z6, Canada. 9. Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. 10. Department of Translational Sciences, Xsphera Biosciences Inc., Boston, MA, USA. 11. Cancer Research Group-School of Life Health and Chemical Sciences, The Open University, Walton Hall, Milton Keynes, MK7 6AA, UK. 12. Department of Urological Sciences and Vancouver Prostate Centre, University of British Columbia, Vancouver, BC, V6H3Z6, Canada. ywang@bccrc.ca. 13. Faculty of Engineering and Natural Sciences, Sabanci University, Orta Mahalle, Üniversite Caddesi No. 27, Orhanlı, Tuzla, Istanbul, 34956, Turkey. milad.ashrafizadeh@sabanciuniv.edu. 14. Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore. apkumar@nus.edu.sg. 15. NUS Centre for Cancer Research (N2CR), Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. apkumar@nus.edu.sg.