Literature DB >> 35524063

Microarray-Based Screening of Putative HSP90 Inhibitors Predicted and Isolated from Microorganisms.

Anusha Kishore1, Artem Fetter1, Carsten Zeilinger2.   

Abstract

Protein microarrays are useful tools for detecting the presence of a target where different prey and bait combinations exist. Here we describe the extended application for a functional target-oriented screening assay with full length Heat shock proteins (HSPs ) for the identification of novel compounds.
© 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  ATP-Cy5; Anti HSP90 inhibitor; Heat shock proteins; Natural products; Protein microarray

Mesh:

Substances:

Year:  2022        PMID: 35524063     DOI: 10.1007/978-1-0716-2273-5_22

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  36 in total

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Authors:  F Ritossa
Journal:  Cell Stress Chaperones       Date:  1996-06       Impact factor: 3.667

Review 2.  Functionality-Independent DNA Encoding of Complex Natural Products.

Authors:  Peixiang Ma; Hongtao Xu; Jie Li; Fengping Lu; Fei Ma; Shuyue Wang; Huan Xiong; Wei Wang; Damiano Buratto; Francesco Zonta; Nan Wang; Kaiwen Liu; Tian Hua; Zhi-Jie Liu; Guang Yang; Richard A Lerner
Journal:  Angew Chem Int Ed Engl       Date:  2019-05-22       Impact factor: 15.336

Review 3.  The HSP90 chaperone machinery.

Authors:  Florian H Schopf; Maximilian M Biebl; Johannes Buchner
Journal:  Nat Rev Mol Cell Biol       Date:  2017-04-21       Impact factor: 94.444

Review 4.  Cellular Handling of Protein Aggregates by Disaggregation Machines.

Authors:  Axel Mogk; Bernd Bukau; Harm H Kampinga
Journal:  Mol Cell       Date:  2018-01-18       Impact factor: 17.970

Review 5.  Peptides in proteins.

Authors:  Benedikt Weber; Andreas Maier; Johannes Buchner
Journal:  J Pept Sci       Date:  2019-12-22       Impact factor: 1.905

6.  Pervasive convergent evolution and extreme phenotypes define chaperone requirements of protein homeostasis.

Authors:  Yasmine Draceni; Sebastian Pechmann
Journal:  Proc Natl Acad Sci U S A       Date:  2019-09-16       Impact factor: 11.205

7.  hsp70: nuclear concentration during environmental stress and cytoplasmic storage during recovery.

Authors:  J M Velazquez; S Lindquist
Journal:  Cell       Date:  1984-03       Impact factor: 41.582

Review 8.  Sorting out the trash: the spatial nature of eukaryotic protein quality control.

Authors:  Emily Mitchell Sontag; Willianne I M Vonk; Judith Frydman
Journal:  Curr Opin Cell Biol       Date:  2014-01-23       Impact factor: 8.382

Review 9.  Stress-Activated Chaperones: A First Line of Defense.

Authors:  Wilhelm Voth; Ursula Jakob
Journal:  Trends Biochem Sci       Date:  2017-09-08       Impact factor: 13.807

10.  Distinct stress conditions result in aggregation of proteins with similar properties.

Authors:  Alan J Weids; Sebastian Ibstedt; Markus J Tamás; Chris M Grant
Journal:  Sci Rep       Date:  2016-04-18       Impact factor: 4.379

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