| Literature DB >> 35524048 |
Zhilan Qian1,2, Qi Liu1,2, Menghao Cai3,4.
Abstract
Fungal natural products have extensive biological activities, and thus have been largely commercialized in the pharmaceutical, agricultural, and food industries. Recently, heterologous expression has become an irreplaceable technique to functionalize fungal biosynthetic gene clusters and synthesize fungal natural products in various chassis organisms. This chapter describes the general method of using Pichia pastoris as a chassis host to investigate fungal biosynthetic pathways.Entities:
Keywords: Biosynthetic pathways; Chassis host; Fungal natural products; Heterologous expression; Pichia pastoris
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Year: 2022 PMID： 35524048 DOI： 10.1007/978-1-0716-2273-5_7
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745