Cesar de la Fuente-Nunez1,2,3. 1. Machine Biology Group, Departments of Psychiatry and Microbiology, Institute for Biomedical Informatics, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. cfuente@upenn.edu. 2. Departments of Bioengineering and Chemical and Biomolecular Engineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA. cfuente@upenn.edu. 3. Penn Institute for Computational Science, University of Pennsylvania, Philadelphia, PA, USA. cfuente@upenn.edu.