| Literature DB >> 35523836 |
Marek Kamiński1, Paweł Marciniak1, Wojciech Tylman1, Rafał Kotas2, Magdalena Janc3, Magdalena Józefowicz-Korczyńska4, Anna Gawrońska4, Ewa Zamysłowska-Szmytke3.
Abstract
Vestibular impairments affect patients' movements and can result in difficulties with daily life activities. The main aim of this study is to answer the question whether a simple and short test such as rotation about a vertical axis can be an objective method of assessing balance dysfunction in patients with unilateral vestibular impairments. A 360˚ rotation test was performed using six MediPost devices. The analysis was performed in three ways: (1) the analytical approach based only on data from one sensor; (2) the analytical approach based on data from six sensors; (3) the artificial neural network (ANN) approach based on data from six sensors. For approaches 1 and 2 best results were obtained using maximum angular velocities (MAV) of rotation and rotation duration (RD), while approach 3 used 11 different features. The following sensitivities and specificities were achieved: for approach 1: MAV-80% and 60%, RD-69% and 74%; for approach 2: 61% and 85% and RD-74% and 56%; for approach 3: 88% and 84%. The ANN-based six-sensor approach revealed the best sensitivity and specificity among parameters studied, however one-sensor approach might be a simple screening test used e.g. for rehabilitation purposes.Entities:
Mesh:
Year: 2022 PMID: 35523836 PMCID: PMC9076858 DOI: 10.1038/s41598-022-11425-z
Source DB: PubMed Journal: Sci Rep ISSN: 2045-2322 Impact factor: 4.996
Figure 1Placement of devices (coloured rectangles) on the body, various configurations: one-device—red or green, six-devices—red, green and blue.
Six-sensor model results based on ROC analysis.
| Parameter | AUC | p | Accuracy (%) | Sensitivity (%) | Specificity (%) |
|---|---|---|---|---|---|
| Latency | 0.59 | 0.13 | 58 | 81 | 37 |
| Maximum angular velocity taking into account all segments | 0.77 | < 0.01 | 74 | 61 | 85 |
| Average angular velocity taking into account all segments | 0.66 | 0.01 | 65 | 72 | 58 |
| Rotation duration | 0.67 | < 0.01 | 65 | 74 | 56 |
Figure 2Example of obtained ROC curves.
Comparison of healthy persons and unhealthy patients according to selected parameters.
| Parameter | Healthy | patients | p-value |
|---|---|---|---|
| Maximum angular velocity | 217.74 ± 55.52 | 173.64 ± 46.38 | < 0.001 |
| Rotation duration | 2.79 ± 0.49 s | 3.37 ± 0.97 s | < 0.001 |
| Length of the trajectory | 94.07 ± 46.46 | 111.39 ± 29.25 | 0.026 |
Single-sensor model results based on ROC analysis.
| Parameter | AUC | p | Accuracy (%) | Sensitivity (%) | Specificity (%) |
|---|---|---|---|---|---|
| Maximum angular velocity | 0.77 | < 0.01 | 73 | 80 | 60 |
| Average angular velocity | 0.56 | 0.28 | 63 | 59 | 66 |
| Rotation duration | 0.75 | < 0.01 | 72 | 69 | 74 |
| Latency | 0.59 | 0.12 | 61 | 29 | 91 |
| Length of the trajectory | 0.70 | < 0.01 | 70 | 71 | 68 |
Six-sensor model classification results. Bold lines indicate best-performing networks.
| Number of hidden layer neurons | AlgorithmA | Number of epochs | Accuracy (%) | Sensitivity (%) | Specificity (%) |
|---|---|---|---|---|---|
| 4 | RMSprop 0.01, 0.7 | 100 | 78 | 83 | 73 |
| 4 | |||||
| 4 | RMSprop 0.01, 0.7 | 400 | 82 | 83 | 82 |
| 5 | RMSprop 0.01, 0.7 | 50 | 81 | 81 | 82 |
| 5 | |||||
| 5 | RMSprop 0.01, 0.7 | 200 | 74 | 69 | 78 |
| 5 | RMSprop 0.01, 0.7 | 1000 | 79 | 83 | 76 |
| 5 | RMSprop 0.001, 0.7 | 100 | 80 | 81 | 80 |
| 5 | |||||
| 5 | RMSprop 0.001, 0.7 | 400 | 80 | 81 | 80 |
| 6 | RMSprop 0.01, 0.7 | 50 | 80 | 81 | 80 |
| 6 | RMSprop 0.01, 0.7 | 100 | 76 | 76 | 76 |
| 6 | |||||
| 6 | SGD 0.01, nesterov | 400 | 80 | 81 | 80 |
AAlgorithm name and parameters: learning rate and momentum coefficient/type.
Comparison of different methodologies for the analysis of rotation (the best results).
| Parameter | Accuracy (%) | Sensitivity (%) | Specificity (%) |
|---|---|---|---|
| Maximum angular velocity, single sensor | 73 | 80 | 60 |
| Maximum angular velocity, taking into account all segments | 74 | 61 | 85 |
| Neural network taking into account all segments | 86 | 88 | 84 |