Literature DB >> 35505023

Photosensitized Oxidation of Intracellular Targets: Understanding the Mechanisms to Improve the Efficiency of Photodynamic Therapy.

Thiago Teixeira Tasso1, Maurício S Baptista2.   

Abstract

The development of improved photosensitizers is a key aspect in the establishment of photodynamic therapy (PDT) as a reliable treatment modality. In this chapter, we discuss how molecular design can lead to photosensitizers with higher selectivity and better efficiency, with focus on the importance of specific intracellular targeting in determining the cell death mechanism and, consequently, the PDT outcome.
© 2022. Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Activatable photosensitizers; Cell death; Drug delivery; Organelle targeting; Photobleaching; Photosensitizer

Mesh：

Substances：

Year:  2022        PMID： 35505023     DOI： 10.1007/978-1-0716-2099-1_18

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  84 in total

Review 1.  Type I and Type II Photosensitized Oxidation Reactions: Guidelines and Mechanistic Pathways.

Authors:  Maurício S Baptista; Jean Cadet; Paolo Di Mascio; Ashwini A Ghogare; Alexander Greer; Michael R Hamblin; Carolina Lorente; Silvia Cristina Nunez; Martha Simões Ribeiro; Andrés H Thomas; Mariana Vignoni; Tania Mateus Yoshimura
Journal:  Photochem Photobiol       Date:  2017-03-27       Impact factor: 3.421

Review 2.  Nanoparticles in photodynamic therapy: an emerging paradigm.

Authors:  Dev Kumar Chatterjee; Li Shan Fong; Yong Zhang
Journal:  Adv Drug Deliv Rev       Date:  2008-09-20       Impact factor: 15.470

Review 3.  New photodynamic therapy with next-generation photosensitizers.

Authors:  Hiromi Kataoka; Hirotada Nishie; Noriyuki Hayashi; Mamoru Tanaka; Akihiro Nomoto; Shigenobu Yano; Takashi Joh
Journal:  Ann Transl Med       Date:  2017-04

4.  Lipofuscin Generated by UVA Turns Keratinocytes Photosensitive to Visible Light.

Authors:  Paulo Newton Tonolli; Orlando Chiarelli-Neto; Carolina Santacruz-Perez; Helena Couto Junqueira; Ii-Sei Watanabe; Felipe Gustavo Ravagnani; Waleska Kerllen Martins; Maurício S Baptista
Journal:  J Invest Dermatol       Date:  2017-07-12       Impact factor: 8.551

Review 5.  New photosensitizers for photodynamic therapy.

Authors:  Heidi Abrahamse; Michael R Hamblin
Journal:  Biochem J       Date:  2016-02-15       Impact factor: 3.857

6.  Photoradiation therapy. II. Cure of animal tumors with hematoporphyrin and light.

Authors:  T J Dougherty; G B Grindey; R Fiel; K R Weishaupt; D G Boyle
Journal:  J Natl Cancer Inst       Date:  1975-07       Impact factor: 13.506

7.  Gold nanorod-photosensitizer complex for near-infrared fluorescence imaging and photodynamic/photothermal therapy in vivo.

Authors:  Boseung Jang; Jin-Young Park; Ching-Hsuan Tung; In-Hoo Kim; Yongdoo Choi
Journal:  ACS Nano       Date:  2011-01-18       Impact factor: 15.881

8.  Photodynamic therapy: novel third-generation photosensitizers one step closer?

Authors:  L B Josefsen; R W Boyle
Journal:  Br J Pharmacol       Date:  2008-03-24       Impact factor: 8.739

Review 9.  Antimicrobial photodynamic inactivation: a bright new technique to kill resistant microbes.

Authors:  Michael R Hamblin
Journal:  Curr Opin Microbiol       Date:  2016-07-13       Impact factor: 7.934

Review 10.  Photodynamic therapy.

Authors:  T J Dougherty; C J Gomer; B W Henderson; G Jori; D Kessel; M Korbelik; J Moan; Q Peng
Journal:  J Natl Cancer Inst       Date:  1998-06-17       Impact factor: 13.506
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