BACKGROUND: Obesity is commonly associated with increased sympathetic tone, changes in heart geometry, and mortality. The aforementioned translates into a higher and potentially modifiable mortality risk for this specific population. OBJECTIVES: The aim of the study was to analyze the extent of changes in the heart ventricular structure following rapid weight loss after bariatric surgery. SETTING: Academic, university-affiliated hospital. METHODS: We retrospectively reviewed all the patients that underwent bariatric surgery at our institution between 2010 and 2015. Data analyzed included demographics, BMI, and associated medical problems. Preoperative and postoperative echography readings were compared looking at the heart geometry, cardiac volumes, and wall thickness. RESULTS: Fifty-one patients who had bariatric surgery and had echocardiography before and after the surgery were identified. There were 33 females (64.7%). The mean age was 63.4 ± 12.0 years with an average BMI of 40.3 ± 6.3. The mean follow-up was 1.2 years after the procedure. At 1 year follow-up 25 patients (49%, p = 0.01) showed normal left ventricular geometry. The left ventricular mass (229 ± 82.1 vs 193.2 ± 42.5, p<0.01) and the left ventricular end diastolic volume (129.4 ± 53 vs 96.4 ± 36.5, p = 0.01) showed a significant modification following the procedure. There was a significant improvement in the interventricular septal thickness (p = 0.01) and relative wall thickness (p < 0.01) following surgery. CONCLUSION: The patients with obesity present a significant cardiac remodeling from concentric remodeling to normal geometry after bariatric surgery. The decrease in BMI has a direct effect on improvement of the left ventricular structure. Further studies must be carried out to define the damage of obesity to diastolic function.
BACKGROUND: Obesity is commonly associated with increased sympathetic tone, changes in heart geometry, and mortality. The aforementioned translates into a higher and potentially modifiable mortality risk for this specific population. OBJECTIVES: The aim of the study was to analyze the extent of changes in the heart ventricular structure following rapid weight loss after bariatric surgery. SETTING: Academic, university-affiliated hospital. METHODS: We retrospectively reviewed all the patients that underwent bariatric surgery at our institution between 2010 and 2015. Data analyzed included demographics, BMI, and associated medical problems. Preoperative and postoperative echography readings were compared looking at the heart geometry, cardiac volumes, and wall thickness. RESULTS: Fifty-one patients who had bariatric surgery and had echocardiography before and after the surgery were identified. There were 33 females (64.7%). The mean age was 63.4 ± 12.0 years with an average BMI of 40.3 ± 6.3. The mean follow-up was 1.2 years after the procedure. At 1 year follow-up 25 patients (49%, p = 0.01) showed normal left ventricular geometry. The left ventricular mass (229 ± 82.1 vs 193.2 ± 42.5, p<0.01) and the left ventricular end diastolic volume (129.4 ± 53 vs 96.4 ± 36.5, p = 0.01) showed a significant modification following the procedure. There was a significant improvement in the interventricular septal thickness (p = 0.01) and relative wall thickness (p < 0.01) following surgery. CONCLUSION: The patients with obesity present a significant cardiac remodeling from concentric remodeling to normal geometry after bariatric surgery. The decrease in BMI has a direct effect on improvement of the left ventricular structure. Further studies must be carried out to define the damage of obesity to diastolic function.
Authors: Surya M Artham; Carl J Lavie; Richard V Milani; Dharmendrakumar A Patel; Anil Verma; Hector O Ventura Journal: Prog Cardiovasc Dis Date: 2009 Sep-Oct Impact factor: 8.194
Authors: Theophilus Owan; Erick Avelar; Kimberly Morley; Ronny Jiji; Nathaniel Hall; Joseph Krezowski; James Gallagher; Zachary Williams; Kevin Preece; Nancy Gundersen; Michael B Strong; Robert C Pendleton; Nathan Segerson; Tom V Cloward; James M Walker; Robert J Farney; Richard E Gress; Ted D Adams; Steven C Hunt; Sheldon E Litwin Journal: J Am Coll Cardiol Date: 2011-02-08 Impact factor: 24.094
Authors: Thomas E Kaier; Douglas Morgan; Julia Grapsa; Ozan M Demir; Stavroula A Paschou; Shweta Sundar; Sherif Hakky; Sanjay Purkayastha; Susan Connolly; Kevin F Fox; Ahmed Ahmed; Jonathan Cousins; Petros Nihoyannopoulos Journal: Eur Heart J Cardiovasc Imaging Date: 2014-06-25 Impact factor: 6.875
Authors: Alan Hinderliter; Andrew Sherwood; Elizabeth C D Gullette; Michael Babyak; Robert Waugh; Anastasia Georgiades; James A Blumenthal Journal: Arch Intern Med Date: 2002-06-24