Literature DB >> 35497516

Synthesis of indole derivatives as prevalent moieties present in selected alkaloids.

Majid M Heravi1, Zahra Amiri1, Kosar Kafshdarzadeh1, Vahideh Zadsirjan1.   

Abstract

Indoles are a significant heterocyclic system in natural products and drugs. They are important types of molecules and natural products and play a main role in cell biology. The application of indole derivatives as biologically active compounds for the treatment of cancer cells, microbes, and different types of disorders in the human body has attracted increasing attention in recent years. Indoles, both natural and synthetic, show various biologically vital properties. Owing to the importance of this significant ring system, the investigation of novel methods of synthesis have attracted the attention of the chemical community. In this review, we aim to highlight the construction of indoles as a moiety in selected alkaloids. This journal is © The Royal Society of Chemistry.

Entities:  

Year:  2021        PMID: 35497516      PMCID: PMC9042329          DOI: 10.1039/d1ra05972f

Source DB:  PubMed          Journal:  RSC Adv        ISSN: 2046-2069            Impact factor:   4.036


  217 in total

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Journal:  Org Biomol Chem       Date:  2006-09-28       Impact factor: 3.876

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6.  First total synthesis of the 7-oxygenated carbazole alkaloids clauszoline-K, 3-formyl-7-hydroxycarbazole, clausine M, clausine N and the anti-HIV active siamenol using a highly efficient palladium-catalyzed approach.

Authors:  Micha P Krahl; Anne Jäger; Tilo Krause; Hans-Joachim Knölker
Journal:  Org Biomol Chem       Date:  2006-07-26       Impact factor: 3.876

7.  Total synthesis of the photoprotecting dipyrrolobenzoquinone (+)-terreusinone.

Authors:  Christy Wang; Jonathan Sperry
Journal:  Org Lett       Date:  2011-11-14       Impact factor: 6.005

8.  Inhibition of human immunodeficiency virus type-1-induced syncytium formation and cytopathicity by complestatin.

Authors:  K Momota; I Kaneko; S Kimura; K Mitamura; K Shimada
Journal:  Biochem Biophys Res Commun       Date:  1991-08-30       Impact factor: 3.575

9.  Lessons from the Total Synthesis of (±) Phalarine: Insights Into the Mechanism of the Pictet-Spengler Reaction.

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Journal:  Pure Appl Chem       Date:  2010-04-06       Impact factor: 2.453

10.  Synthesis and antifungal activity of 3-(1,3,4-oxadiazol-5-yl)-indoles and 3-(1,3,4-oxadiazol-5-yl)methyl-indoles.

Authors:  Ming-Zhi Zhang; Nick Mulholland; David Beattie; Dianne Irwin; Yu-Cheng Gu; Qiong Chen; Guang-Fu Yang; John Clough
Journal:  Eur J Med Chem       Date:  2013-02-09       Impact factor: 6.514

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