| Literature DB >> 35497074 |
Emma Curran1, Michael Rosato1, Finola Ferry1, Gerard Leavey1.
Abstract
The COVID-19 pandemic has affected mental health and social connections. Older people may be disproportionately affected, placing them at increased risk for complex mental ill-health outcomes and quality of life undermined by anxiety and depression. Understanding gender differences in the determinants of anxiety and depression symptoms is crucial to policy and practice. This study aims to examine gender-specific symptom subtypes (and subthreshold symptoms) in an older English population sampled during the COVID period, in relation to their socio-demographic, social, and health circumstances. The sample comprises all individuals aged 50 years or older and included in the English Longitudinal Study of Ageing COVID-19 sub-study conducted during June-July 2020. Latent class analysis (LCA) defined indicative sample subgroups of clinically relevant anxiety and depression. Multinomial logistic regression assessed associations between socio-demographic characteristics, health and social care indicators, loneliness, and pre-pandemic mental ill-health. LCA derived three classes of self-reported depression and anxiety: for females (1) comorbid depression and anxiety (19.9% of the sample), (2) depression and subthreshold anxiety (31.6%), and (3) no or low symptoms of depression and anxiety (48.5%), and for males (1) comorbid depression and anxiety (12.8%), (2) subthreshold anxiety and depression (29.6%), and (3) no or low depression and anxiety (57.6%). Multinomial logistic regression analyses indicate that compared to those with low/no mental health symptoms, severity of pandemic-era mental ill-health was positively associated with pre-pandemic mental health levels, worry over finances, having access to essentials, loneliness, and access to health and social care services. Findings support the persistence of comorbidity of both depression and anxiety in the pandemic period. Results may inform government health strategy on interventions to prevent social isolation and mitigate the effects of the pandemic on deteriorating mental health in older people who may be more susceptible.Entities:
Year: 2022 PMID: 35497074 PMCID: PMC9041280 DOI: 10.1007/s11469-022-00820-2
Source DB: PubMed Journal: Int J Ment Health Addict ISSN: 1557-1874 Impact factor: 11.555
Frequency of depressive or anxiety symptoms and percentages within gender as measured in the depression (CES-D) and anxiety (HADS-A), reported in the COVID-19 Sub-study of the English Longitudinal Study of Ageing (ELSA)
| Total sample 7040 | Males | Females | |
|---|---|---|---|
| Questions from the CES-D$ depression subscale | |||
| You felt depressed | 1232 (17.5) | 432 (14.1) | 800 (20.1) |
| You felt that everything you did was an effort | 1684 (23.9) | 585 (19.1) | 1099 (27.6) |
| Your sleep was restless | 3159 (44.9) | 1203 (39.3) | 1956 (49.3) |
| You were not happy | 1113 (15.8) | 387 (12.7) | 726 (18.4) |
| You felt lonely | 1209 (17.2) | 342 (11.2) | 867 (21.9) |
| You did not enjoy life | 1291 (18.3) | 431 (14.1) | 860 (21.8) |
| You felt sad | 411 (5.8) | 121 (17.5) | 290 (30.5) |
| You could not get going | 1931 (27.4) | 666 (21.8) | 1265 (31.9) |
| Questions from the HADS-A% anxiety subscale | |||
| Feeling nervous, anxious or on edge | 2572 (36.5) | 832 (27.3) | 1740 (43.9) |
| Not being able to stop or control worrying | 1855 (26.3) | 564 (18.5) | 1291 (32.6) |
| Worrying too much about different things | 2546 (36.2) | 838 (27.5) | 1708 (43.2) |
| Trouble relaxing | 2414 (34.3) | 857 (28.1) | 1557 (39.5) |
| Being so restless that it is hard to sit still | 1721 (24.4) | 603 (19.8) | 1118 (28.3) |
| Becoming easily annoyed or irritable | 2688 (38.2) | 1043 (34.2) | 1645 (41.5) |
| Feeling afraid as if something awful might happen | 1868 (26.5) | 589 (19.3) | 1279 (32.3) |
$Depressive symptoms assessed using the 8-item Centre for Epidemiologic Studies-Depression (CES-D) which assesses symptoms experienced in the 7 days preceding the survey (Radloff, 1977)
%Anxiety symptoms assessed using the anxiety subscale of the Hospital Anxiety and Depression Scale (HADS-A), which measures the presence of anxiety symptoms with no specific time frame (Zigmond & Snaith, 1983)
Fit indices of the LCA to profile depression and anxiety symptoms in males and females
| Model 2a | Log | Free | AIC | BIC | SSABIC | LRT | Entropy | |
| 1 Class males | − 23,414 | 30 | 46,889 | 47,067 | 46,971 | |||
| 2 Class males | − 18,464 | 61 | 37,050 | 37,412 | 37,218 | 9859 | 0.00 | 0.93 |
| 4 Class males | − 17,296 | 123 | 34,838 | 35,567 | 35,177 | 643 | 0.75 | 0.88 |
| 5 Class males | − 17,071 | 154 | 34,451 | 35,365 | 34,876 | 446 | 0.26 | 0.86 |
| 6 Class males | − 16,931 | 185 | 34,233 | 35,331 | 34,743 | 278 | 0.76 | 0.84 |
| Model 2b | Log | Free | AIC | BIC | SSABIC | LRT | Entropy | |
| 1 Class females | − 34,488 | 15 | 69,006 | 69,100 | 69,052 | |||
| 2 Class females | − 26,933 | 31 | 53,928 | 54,122 | 54,024 | 14,996 | 0.00 | 0.92 |
| 4 Class females | − 25,400 | 63 | 50,926 | 51,321 | 51,121 | 866 | 0.10 | 0.81 |
| 5 Class females | − 25,196 | 79 | 50,550 | 51,045 | 50,794 | 405 | 0.09 | 0.79 |
| 6 Class females | − 25,024 | 95 | 50,238 | 50,834 | 50,532 | 340 | 0.02 | 0.79 |
Log log likelihood function, maximum likelihood estimation; Free free parameters, LRX2 likelihood ratio chi-square, AIC Akaike information criteria, BIC Bayesian information criteria, SSABIC sample size adjusted BIC, LRT Lo-Mendell-Rubin adjusted likelihood ratio test. *Denotes most parsimonious model
Fig. 1The 3-class solution (males) — this comprises (1) comorbid depression and anxiety (MAD) (12.8% of the sample), with a high probability of reporting symptoms of both depression and anxiety; (2) subthreshold anxiety and depression (29.6%); and (3) no or low depression and anxiety symptoms (57.6%)
Fig. 2The 3-class solution (females) — this comprises (1) comorbid depression and anxiety (MAD) (19.9% of the sample), with a high probability of reporting symptoms of depression and anxiety; (2) depression and subthreshold anxiety (31.6%); and (3) no or low depression and anxiety symptoms [48.5%]
Male LCA groups and regression adjusted for age and housing tenure
| Comorbid depression and anxiety (MAD) | Subthreshold depression and anxiety | ||||
|---|---|---|---|---|---|
| M1 | M2 | M3 | M4 | ||
| Ethnicity | Not minority ethnic Minority ethnic group | 1.00 0.49 (0.13, 1.91) | 1.00 0.39 (0.12, 1.29) | 1.00 0.56 (0.28, 1.11) | 1.00 |
| Health care needs met | No care needs Always met Mostly met Sometimes met Hardly ever met | 1.00 | 1.00 1.19 (0.27, 5.18) | 1.00 0.90 (0.47, 1.75) 0.47 (0.14, 1.56) 1.61 (0.42, 6.15) | 1.00 1.33 (0.93, 1.91) 0.90 (0.43, 1.89) 0.27 (0.06, 1.12) 3.07 (0.73, 12.96) |
| Accessed community HSC services | Didn’t need to contact Didn’t attempt contact Yes No | 1.00 1.03 (0.62, 1.72) 0.71 (0.41, 1.24) | 1.00 0.91 (0.55, 1.50) 0.88 (0.51, 1.54) | 1.00 1.40 (0.94, 2.09) 1.14 (0.80, 1.62) | 1.00 1.51 (0.98, 2.32) 1.02 (0.70, 1.49) |
| Worry about finances | Not at all worried Somewhat worried Very worried | 1.00 1.25 (0.78, 1.99) | 1.00 1.16 (0.70, 1.93) | 1.00 1.22 (0.92, 1.63) | 1.00 1.11 (0.82, 1.49) |
| Worry about having essentials | Not at all worried Somewhat worried Very worried | 1.00 | 1.00 1.50 (0.89, 2.52) | 1.00 | 1.00 |
| Partner in household | No Yes | 1.00 | 1.00 | ||
| UCLA loneliness | Scale 0–12 | ||||
| Depression at wave 9 (pre C-19) | No Yes | 1.00 | 1.00 | ||
*Denotes significant p-value
Female LCA groups and regression adjusted for age and housing tenure
| Comorbid depression and anxiety (MAD) | Depression and subthreshold-anxiety | ||||
|---|---|---|---|---|---|
| M1 | M2 | M3 | M4 | ||
| Ethnicity | Not minority ethnic Minority ethnic group | 1.00 | 1.00 | 1.00 1.09 (0.68, 1.75) | 1.00 1.08 (0.62, 1.88) |
| Health care needs met | No care needs Always met Mostly met Sometimes met Hardly ever met | 1.00 | 1.00 1.36 (0.84, 2.18) 2.40 (0.80, 7.19) 1.75 (0.32, 9.70) | 1.00 1.41 (0.85, 2.33) 0.93 (0.30, 2.88) 1.53 (0.44, 5.27) | 1.00 1.33 (0.81, 2.20) 0.53 (0.11, 2.59) 1.42 (0.33, 6.08) |
| Accessed community HSC services | Didn’t need to contact Didn’t attempt contact Yes No | 1.00 | 1.00 1.20 (0.78, 1.85) | 1.00 0.96 (0.68, 1.38) 1.19 (0.89, 1.59) | 1.00 1.21 (0.89, 1.64) 0.83 (0.57, 1.20) 1.00 (0.73, 1.36) |
| Worry about finances | Not at all worried Somewhat worried Very worried | 1.00 | 1.00 | 1.00 1.12 (0.89, 1.41) | 1.00 1.21 (0.95, 1.54) |
| Worry about having essentials | Not at all worried Somewhat worried Very worried | 1.00 | 1.00 | 1.00 | 1.00 |
| Partner in household | No Yes | 1.00 | 1.00 | ||
| UCLA loneliness | Scale 0–12 | ||||
| Depression at wave 9 (pre C-19) | No Yes | 1.00 | 1.00 | ||
*Denotes significant p-value