Literature DB >> 35493625

Do screening tools assess palliative care needs and 12-month mortality in patients admitted to hepatology in-patient wards?

Joseph Low1, Catherine Carroll2, Jo Wilson2, Rachel Craig2, Shree Vadera3, Sara Cococcia3,4, Douglas Thorburn3, Patrick Stone1, Aileen Marshall3, Victoria Vickerstaff1.   

Abstract

Background: Many liver patients have unmet palliative care needs, but liver clinicians are unclear whom to refer to specialist palliative care (SPC). The Supportive and Palliative Care Indicator Tool (SPICT) and the Bristol Prognostic Screening Tool (BPST) could help identify suitable patients, but neither has been tested for this role. This study evaluated their role as screening tools for palliative care needs and for predicting 12-month mortality.
Methods: A case note review of hepatology in-patients, who were not peritransplant and post-transplant status, was conducted in one tertiary unit. Main outcomes were clinical judgement of need for SPC referral, BPST scores, SPICT attribution of caseness and 12-month survival status. Discriminatory ability of tools was assessed using sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and area under the receiver operating characteristic (AUROC) curve.
Results: 117 medical notes were reviewed for survival analysis, 47 of which were additionally assessed for suitability for SPC referral, using clinical judgement. SPICT (sensitivity=93%; PPV=93%; AUROC=0.933) and BPST (sensitivity=59%, PPV=79%, AUROC=0.693) demonstrated excellent and good performance, respectively, in predicting patients' need for SPC referral. SPICT and BPST only had moderate ability at predicting death at 12 months (PPV: 54% and 56%, respectively).
Conclusion: SPICT and BPST show potential as screening tools for identifying patients for referral to SPC. Further work is needed to determine how to implement these tools in a clinical setting. © Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  chronic liver disease; cirrhosis; health service research; screening

Year:  2021        PMID: 35493625      PMCID: PMC8996104          DOI: 10.1136/flgastro-2020-101709

Source DB:  PubMed          Journal:  Frontline Gastroenterol        ISSN: 2041-4137


  14 in total

1.  Integration of palliative and supportive care in the management of advanced liver disease: development and evaluation of a prognostic screening tool and supportive care intervention.

Authors:  Benjamin E Hudson; Kelly Ameneshoa; Anya Gopfert; Rachael Goddard; Karen Forbes; Julia Verne; Peter Collins; Fiona Gordon; Andrew J Portal; Colette Reid; C Anne McCune
Journal:  Frontline Gastroenterol       Date:  2016-10-05

Review 2.  The burden of liver disease in Europe: a review of available epidemiological data.

Authors:  Martin Blachier; Henri Leleu; Markus Peck-Radosavljevic; Dominique-Charles Valla; Françoise Roudot-Thoraval
Journal:  J Hepatol       Date:  2013-03       Impact factor: 25.083

3.  Changing end-of-life care practice for liver transplant service patients: structured palliative care intervention in the surgical intensive care unit.

Authors:  Sangeeta Lamba; Patricia Murphy; Susan McVicker; Janet Harris Smith; Anne C Mosenthal
Journal:  J Pain Symptom Manage       Date:  2012-07-04       Impact factor: 3.612

4.  Benefit of Early Palliative Care Intervention in End-Stage Liver Disease Patients Awaiting Liver Transplantation.

Authors:  Alexandra J Baumann; David S Wheeler; Marva James; Roberta Turner; Arthur Siegel; Victor J Navarro
Journal:  J Pain Symptom Manage       Date:  2015-08-22       Impact factor: 3.612

Review 5.  The global burden of liver disease: the major impact of China.

Authors:  Fu-Sheng Wang; Jian-Gao Fan; Zheng Zhang; Bin Gao; Hong-Yang Wang
Journal:  Hepatology       Date:  2014-10-29       Impact factor: 17.425

6.  Palliative Care for Patients with End-Stage Liver Disease on the Liver Transplant Waiting List: An International Systematic Review.

Authors:  Shan Shan Vijeratnam; Bridget Candy; Rachel Craig; Aileen Marshall; Patrick Stone; Joseph T S Low
Journal:  Dig Dis Sci       Date:  2021-01-12       Impact factor: 3.199

Review 7.  Addressing liver disease in the UK: a blueprint for attaining excellence in health care and reducing premature mortality from lifestyle issues of excess consumption of alcohol, obesity, and viral hepatitis.

Authors:  Roger Williams; Richard Aspinall; Mark Bellis; Ginette Camps-Walsh; Matthew Cramp; Anil Dhawan; James Ferguson; Dan Forton; Graham Foster; Ian Gilmore; Matthew Hickman; Mark Hudson; Deirdre Kelly; Andrew Langford; Martin Lombard; Louise Longworth; Natasha Martin; Kieran Moriarty; Philip Newsome; John O'Grady; Rachel Pryke; Harry Rutter; Stephen Ryder; Nick Sheron; Tom Smith
Journal:  Lancet       Date:  2014-11-29       Impact factor: 79.321

8.  Palliative Care and Health Care Utilization for Patients With End-Stage Liver Disease at the End of Life.

Authors:  Arpan A Patel; Anne M Walling; Joni Ricks-Oddie; Folasade P May; Sammy Saab; Neil Wenger
Journal:  Clin Gastroenterol Hepatol       Date:  2017-02-04       Impact factor: 13.576

9.  Managing uncertainty in advanced liver disease: a qualitative, multiperspective, serial interview study.

Authors:  Barbara Kimbell; Kirsty Boyd; Marilyn Kendall; John Iredale; Scott A Murray
Journal:  BMJ Open       Date:  2015-11-19       Impact factor: 2.692

10.  Advanced chronic liver disease in the last year of life: a mixed methods study to understand how care in a specialist liver unit could be improved.

Authors:  Joseph Low; Sarah Davis; Victoria Vickerstaff; Lynda Greenslade; Katherine Hopkins; Andrew Langford; Aileen Marshall; Douglas Thorburn; Louise Jones
Journal:  BMJ Open       Date:  2017-08-29       Impact factor: 2.692

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  1 in total

1.  Palliative Care, Patient-Reported Measures, and Outcomes in Hospitalized Patients With Cirrhosis.

Authors:  Eric S Orman; Andrew Yousef; Chenjia Xu; Hani Shamseddeen; Amy W Johnson; Lauren Nephew; Marwan Ghabril; Archita P Desai; Kavish R Patidar; Naga Chalasani
Journal:  J Pain Symptom Manage       Date:  2022-02-21       Impact factor: 5.576

  1 in total

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