Literature DB >> 35493062

Automatic Detection of Alzheimer's Disease Using Spontaneous Speech Only.

Jun Chen1, Jieping Ye1, Fengyi Tang2, Jiayu Zhou2.   

Abstract

Alzheimer's disease (AD) is a neurodegenerative syndrome which affects tens of millions of elders worldwide. Although there is no treatment currently available, early recognition can improve the lives of people with AD and their caretakers and families. To find a cost-effective and easy-to-use method for dementia detection and address the dementia classification task of InterSpeech 2021 ADReSSo (Alzheimer's' Dementia Recognition through Spontaneous Speech only) challenge, we conduct a systematic comparison of approaches to detection of cognitive impairment based on spontaneous speech. We investigated the characteristics of acoustic modality and linguistic modality directly based on the audio recordings of narrative speech, and explored a variety of modality fusion strategies. With an ensemble over top-10 classifiers on the training set, we achieved an accuracy of 81.69% compared to the baseline of 78.87% on the test set. The results suggest that although transcription errors will be introduced through automatic speech recognition, integrating textual information generally improves classification performance. Besides, ensemble methods can boost both the accuracy and the robustness of models.

Entities:  

Keywords:  Alzheimer’s Disease; Cognitive Decline Detection; Computational Paralinguistics; Modality Fusion

Year:  2021        PMID: 35493062      PMCID: PMC9056005          DOI: 10.21437/interspeech.2021-2002

Source DB:  PubMed          Journal:  Interspeech        ISSN: 2308-457X


  6 in total

1.  "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician.

Authors:  M F Folstein; S E Folstein; P R McHugh
Journal:  J Psychiatr Res       Date:  1975-11       Impact factor: 4.791

2.  The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment.

Authors:  Ziad S Nasreddine; Natalie A Phillips; Valérie Bédirian; Simon Charbonneau; Victor Whitehead; Isabelle Collin; Jeffrey L Cummings; Howard Chertkow
Journal:  J Am Geriatr Soc       Date:  2005-04       Impact factor: 5.562

3.  Prosodic impairment in Alzheimer's disease: assessment and clinical relevance.

Authors:  Giuseppe Tosto; M Gasparini; G L Lenzi; G Bruno
Journal:  J Neuropsychiatry Clin Neurosci       Date:  2011       Impact factor: 2.198

4.  The natural history of Alzheimer's disease. Description of study cohort and accuracy of diagnosis.

Authors:  J T Becker; F Boller; O L Lopez; J Saxton; K L McGonigle
Journal:  Arch Neurol       Date:  1994-06

5.  A Speech Recognition-based Solution for the Automatic Detection of Mild Cognitive Impairment from Spontaneous Speech.

Authors:  Laszlo Toth; Ildiko Hoffmann; Gabor Gosztolya; Veronika Vincze; Greta Szatloczki; Zoltan Banreti; Magdolna Pakaski; Janos Kalman
Journal:  Curr Alzheimer Res       Date:  2018       Impact factor: 3.498

6.  Automatic dementia screening and scoring by applying deep learning on clock-drawing tests.

Authors:  Shuqing Chen; Daniel Stromer; Harb Alnasser Alabdalrahim; Stefan Schwab; Markus Weih; Andreas Maier
Journal:  Sci Rep       Date:  2020-11-30       Impact factor: 4.379

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.