| Literature DB >> 35488145 |
Yan Gao1,2,3, Ye Li1,2, Xueting Duan1,2, Qian Wang4,5,6, Haisong Zhang7,8,9.
Abstract
Indoxyl sulphate (IS) a representative uraemic toxin in the blood of patients with chronic kidney disease (CKD). Its accumulation may be closely related to CKD and the increasing morbidity and mortality of the disease's related complications. Timely and effective detection of the IS level and efficient clearance of IS may effectively prevent the progression of CKD and its related complications. Therefore, this article summarizes the research progress of IS related, including IS in CKD and its associated complications including chronic kidney disease, chronic kidney disease with cardiovascular disease, renal anemia, bone mineral metabolic disease and neuropsychiatric disorders, looking for IS accurate rapid detection methods, and explore the efficient treatment to reduce blood levels of indole phenol sulphate.Entities:
Keywords: Chronic kidney disease; Complication; Indoxyl sulphate; Research progress
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Year: 2022 PMID： 35488145 DOI： 10.1007/s11255-022-03209-1
Source DB: PubMed Journal: Int Urol Nephrol ISSN： 0301-1623 Impact factor: 2.266