Literature DB >> 35481328

A Case of Bilateral Adrenal Hemorrhage: The Exceptional Cause of Adrenal Insufficiency.

Aemen S Khakwani1, Fatima Waqar2, Usman A Khan3, Muhammad Nadeem Anwar4.   

Abstract

Bilateral adrenal hemorrhage is an extremely uncommon and life-threatening condition. It is caused by multiple etiologies, including antiphospholipid syndrome, disseminated histoplasmosis, trauma, severe stress, and granulomatous disease. The authors present a unique case of a 64-year-old alcoholic male, who was admitted after fall and right hip fracture. On day seven of admission, the patient started to develop hypotension, leukocytosis, and tachycardia. CT abdomen was done, which ruled out infectious causes, however, it showed bilateral adrenal hemorrhages. Patient adrenocorticotrophic hormone (ACTH) stimulation test was positive for adrenal insufficiency and was started on hydrocortisone replacement. Our case highlights the fact that adrenal insufficiency after bilateral adrenal hemorrhage can be slow and can manifest as late as seven days and prompt therapy with steroids is warranted to avoid life-threatening adrenal insufficiency.
Copyright © 2022, Khakwani et al.

Entities:  

Keywords:  acth; bilateral adrenal haemorrhage; hydrocortisone; primary adrenal insufficiency; serum cortisol

Year:  2022        PMID: 35481328      PMCID: PMC9033516          DOI: 10.7759/cureus.23413

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  7 in total

1.  Spontaneous idiopathic bilateral massive adrenal hemorrhage in an elderly woman.

Authors:  Enrique Antón
Journal:  J Am Geriatr Soc       Date:  2009-12       Impact factor: 5.562

2.  Definitive adrenal insufficiency due to bilateral adrenal hemorrhage and primary antiphospholipid syndrome.

Authors:  P Caron; M H Chabannier; J P Cambus; F Fortenfant; P Otal; J M Suc
Journal:  J Clin Endocrinol Metab       Date:  1998-05       Impact factor: 5.958

Review 3.  Bilateral massive adrenal hemorrhage.

Authors:  R H Rao
Journal:  Med Clin North Am       Date:  1995-01       Impact factor: 5.456

4.  Adrenal hemorrhage during anticoagulant therapy.

Authors:  F D McDonald; A R Myers; R Pardo
Journal:  JAMA       Date:  1966-12-05       Impact factor: 56.272

5.  Adrenal hemorrhage: a 25-year experience at the Mayo Clinic.

Authors:  A Vella; T B Nippoldt; J C Morris
Journal:  Mayo Clin Proc       Date:  2001-02       Impact factor: 7.616

6.  Adrenal haemorrhage due to heparin-induced thrombocytopenia.

Authors:  Siva Ketha; Patrick Smithedajkul; Adrian Vella; Rajiv Pruthi; Waldemar Wysokinski; Robert McBane
Journal:  Thromb Haemost       Date:  2013-02-07       Impact factor: 5.249

Review 7.  Clinical update on the management of adrenal hemorrhage.

Authors:  Daniel R Simon; Michael A Palese
Journal:  Curr Urol Rep       Date:  2009-01       Impact factor: 3.092

  7 in total

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