Literature DB >> 35481325

Amlodipine-Induced Liver Injury.

Julian Yet Kwong Horman1, Puja Patel2, Michael Schultz1, Jennifer Kraschnewski2.   

Abstract

This is a case of an 88-year-old female with a history of hypertension who was started on amlodipine about three weeks prior to presentation. After about two weeks of amlodipine therapy, she developed intermittent right upper quadrant pain as well as pruritus which continued for a few days before she presented to medical attention. Her labs showed significantly elevated liver enzymes so she presented to the hospital for further evaluation. Imaging was unremarkable, her infectious and autoimmune workups were all negative. The amlodipine was discontinued and her liver enzymes slowly normalized after about seven weeks.
Copyright © 2022, Yet Kwong Horman et al.

Entities:  

Keywords:  amlodipine; amlodipine liver injury; drug induced liver injury; hypertension; idiosyncratic liver injury

Year:  2022        PMID: 35481325      PMCID: PMC9034656          DOI: 10.7759/cureus.23441

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  8 in total

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Authors:  Einar S Björnsson
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Journal:  J Hepatol       Date:  2019-03-27       Impact factor: 25.083

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Authors:  I Osterloh
Journal:  Am Heart J       Date:  1989-11       Impact factor: 4.749

4.  ACG Clinical Guideline: Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury.

Authors:  Naga P Chalasani; Haripriya Maddur; Mark W Russo; Robert J Wong; K Rajender Reddy
Journal:  Am J Gastroenterol       Date:  2021-05-01       Impact factor: 10.864

5.  Intrinsic versus idiosyncratic drug-induced hepatotoxicity--two villains or one?

Authors:  Robert A Roth; Patricia E Ganey
Journal:  J Pharmacol Exp Ther       Date:  2009-12-17       Impact factor: 4.030

6.  2020 International Society of Hypertension Global Hypertension Practice Guidelines.

Authors:  Thomas Unger; Claudio Borghi; Fadi Charchar; Nadia A Khan; Neil R Poulter; Dorairaj Prabhakaran; Agustin Ramirez; Markus Schlaich; George S Stergiou; Maciej Tomaszewski; Richard D Wainford; Bryan Williams; Aletta E Schutte
Journal:  Hypertension       Date:  2020-05-06       Impact factor: 10.190

Review 7.  Drug-induced liver injury: recent advances in diagnosis and risk assessment.

Authors:  Gerd A Kullak-Ublick; Raul J Andrade; Michael Merz; Peter End; Andreas Benesic; Alexander L Gerbes; Guruprasad P Aithal
Journal:  Gut       Date:  2017-03-23       Impact factor: 23.059

8.  Comprehension of Top 200 Prescribed Drugs in the US as a Resource for Pharmacy Teaching, Training and Practice.

Authors:  Andrea V Fuentes; Moises D Pineda; Kalyan C Nagulapalli Venkata
Journal:  Pharmacy (Basel)       Date:  2018-05-14
  8 in total

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