Literature DB >> 35478085

Outcomes of prolonged mechanical ventilation and tracheostomy in critically ill elderly patients: a historical cohort study.

Tiffany Lee1, Qiao Li Tan1,2, Tasnim Sinuff3, Alex Kiss4, Sangeeta Mehta5.   

Abstract

PURPOSE: With an aging global population, the increased proportion of elderly patients in the intensive care unit (ICU) raises important questions regarding optimal management. Currently, data on tracheostomy and its outcomes in the elderly are limited. We aimed to determine the in-hospital survival of elderly ICU patients following tracheostomy, and describe impacts on discharge disposition and functional outcomes.
METHODS: We conducted a historical cohort study at two academic hospitals in Toronto. All patients aged ≥ 70 yr who received a tracheostomy during their ICU stay between January 2010 and June 2016 were included in a retrospective chart review. Data on patient demographics, frailty, tracheostomy indication, and outcomes were collected.
RESULTS: The study included 270 patients with a mean (standard deviation) age of 81 (6) yr. The majority were admitted to ICU for respiratory failure (147/270, 54%) and received a tracheostomy for prolonged mechanical ventilation (202/270, 75%). Intensive care unit and hospital mortality were 26% (68/270) and 46% (125/270), respectively. Twenty-five percent (67/270) of patients were decannulated during hospital admission, a median [interquartile range (IQR)] of 41 [25-68] days after tracheostomy. Intensive care unit and hospital length of stay were 31 [17-53] and 81 [46-121] days, respectively. At hospital discharge, 6% (17/270) of patients were discharged home, all were frail (median Clinical Frailty Score of 7) and most were tube-fed (101/270, 70%), unable to speak (81/270, 56%), and nonambulatory (98/270, 68%).
CONCLUSIONS: In patients aged ≥ 70 yr, tracheostomy during ICU stay marked a transition toward prolonged chronic critical illness. Nearly half of the patients died during the admission, and although a quarter were successfully decannulated, the majority of survivors were left with severe frailty and functional impairment.
© 2022. Canadian Anesthesiologists' Society.

Entities:  

Keywords:  elderly; frailty; mechanical ventilation; outcomes; tracheostomy

Mesh:

Year:  2022        PMID: 35478085     DOI: 10.1007/s12630-022-02263-8

Source DB:  PubMed          Journal:  Can J Anaesth        ISSN: 0832-610X            Impact factor:   6.713


  44 in total

1.  What's new in intensive care: tracheostomy-what is known and what remains to be determined.

Authors:  José Aquino Esperanza; Paolo Pelosi; Lluís Blanch
Journal:  Intensive Care Med       Date:  2019-08-26       Impact factor: 17.440

2.  Impact of tracheotomy on sedative administration, sedation level, and comfort of mechanically ventilated intensive care unit patients.

Authors:  Ania Nieszkowska; Alain Combes; Charles-Edouard Luyt; Hichem Ksibi; Jean-Louis Trouillet; Claude Gibert; Jean Chastre
Journal:  Crit Care Med       Date:  2005-11       Impact factor: 7.598

Review 3.  Tracheostomy practice in adults with acute respiratory failure.

Authors:  Bradley D Freeman; Peter E Morris
Journal:  Crit Care Med       Date:  2012-10       Impact factor: 7.598

4.  Early tracheostomy in trauma patients saves time and money.

Authors:  Glendon A Hyde; Stephanie A Savage; Ben L Zarzaur; Jensen E Hart-Hyde; Candace B Schaefer; Martin A Croce; Timothy C Fabian
Journal:  Injury       Date:  2014-09-16       Impact factor: 2.586

5.  Early tracheostomy decreases ventilation time but has no impact on mortality of intensive care patients: a randomized study.

Authors:  Tillo Koch; Birgit Hecker; Andreas Hecker; Florian Brenck; Matthias Preuß; Thorsten Schmelzer; Winfried Padberg; Markus A Weigand; Joachim Klasen
Journal:  Langenbecks Arch Surg       Date:  2012-02-10       Impact factor: 3.445

6.  Outcome of mechanically ventilated patients who require a tracheostomy.

Authors:  Fernando Frutos-Vivar; Andrés Esteban; Carlos Apezteguía; Antonio Anzueto; Peter Nightingale; Marco González; Luis Soto; Carlos Rodrigo; Jean Raad; Cide M David; Dimitros Matamis; Gabriel D' Empaire
Journal:  Crit Care Med       Date:  2005-02       Impact factor: 7.598

7.  Clinical outcomes for the elderly patient receiving a tracheotomy.

Authors:  Jonathan Zvi Baskin; Georgia Panagopoulos; Christine Parks; Stephen Rothstein; Arnold Komisar
Journal:  Head Neck       Date:  2004-01       Impact factor: 3.147

8.  Trends in Tracheostomy for Mechanically Ventilated Patients in the United States, 1993-2012.

Authors:  Anuj B Mehta; Sohera N Syeda; Lisa Bajpayee; Colin R Cooke; Allan J Walkey; Renda Soylemez Wiener
Journal:  Am J Respir Crit Care Med       Date:  2015-08-15       Impact factor: 21.405

9.  Characteristics, management, and in-hospital mortality among patients with severe sepsis in intensive care units in Japan: the FORECAST study.

Authors:  Toshikazu Abe; Hiroshi Ogura; Atsushi Shiraishi; Shigeki Kushimoto; Daizoh Saitoh; Seitaro Fujishima; Toshihiko Mayumi; Yasukazu Shiino; Taka-Aki Nakada; Takehiko Tarui; Toru Hifumi; Yasuhiro Otomo; Kohji Okamoto; Yutaka Umemura; Joji Kotani; Yuichiro Sakamoto; Junichi Sasaki; Shin-Ichiro Shiraishi; Kiyotsugu Takuma; Ryosuke Tsuruta; Akiyoshi Hagiwara; Kazuma Yamakawa; Tomohiko Masuno; Naoshi Takeyama; Norio Yamashita; Hiroto Ikeda; Masashi Ueyama; Satoshi Fujimi; Satoshi Gando
Journal:  Crit Care       Date:  2018-11-22       Impact factor: 9.097

10.  Effect of early vs late tracheostomy placement on survival in patients receiving mechanical ventilation: the TracMan randomized trial.

Authors:  Duncan Young; David A Harrison; Brian H Cuthbertson; Kathy Rowan
Journal:  JAMA       Date:  2013-05-22       Impact factor: 56.272

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  1 in total

1.  Association Between Tracheostomy and Functional, Neuropsychological, and Healthcare Utilization Outcomes in the RECOVER Cohort.

Authors:  Sangeeta Mehta; Anita Brondani; George Tomlinson; Leslie Chu; Stacey Burns; Andrea Matte; Jill I Cameron; Jan O Friedrich; Jill Rudkowski; Priscila Robles; Yoanna Skrobik; Margaret Herridge; Neill K J Adhikari
Journal:  Crit Care Explor       Date:  2022-10-07
  1 in total

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