Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Structural basis for pore blockade of human voltage-gated calcium channel Cav1.3 by motion sickness drug cinnarizine.

Literature DB >> 35477996

Structural basis for pore blockade of human voltage-gated calcium channel Ca_v1.3 by motion sickness drug cinnarizine.

Xia Yao¹, Shuai Gao², Nieng Yan³.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 2022 PMID： 35477996 PMCID： PMC9525318 DOI： 10.1038/s41422-022-00663-5

Source DB: PubMed Journal: Cell Res ISSN： 1001-0602 Impact factor: 46.297

Keyword Cloud
References

× No keyword cloud information.

15 in total

Review 1. Structure and regulation of voltage-gated Ca2+ channels.

Authors: W A Catterall
Journal: Annu Rev Cell Dev Biol Date: 2000 Impact factor: 13.827

Review 2. The ß subunit of voltage-gated Ca2+ channels.

Authors: Zafir Buraei; Jian Yang
Journal: Physiol Rev Date: 2010-10 Impact factor: 37.312

3. A Single Amino Acid Determines the Selectivity and Efficacy of Selective Negative Allosteric Modulators of Ca_V1.3 L-Type Calcium Channels.

Authors: Garry Cooper; Soosung Kang; Tamara Perez-Rosello; Jaime N Guzman; Daniel Galtieri; Zhong Xie; Jyothisri Kondapalli; Jack Mordell; Richard B Silverman; D James Surmeier
Journal: ACS Chem Biol Date: 2020-09-03 Impact factor: 5.100

4. Closed-state inactivation and pore-blocker modulation mechanisms of human Ca_V2.2.

Authors: Yanli Dong; Yiwei Gao; Shuai Xu; Yuhang Wang; Zhuoya Yu; Yue Li; Bin Li; Tian Yuan; Bei Yang; Xuejun Cai Zhang; Daohua Jiang; Zhuo Huang; Yan Zhao
Journal: Cell Rep Date: 2021-11-02 Impact factor: 9.423

Review 5. Pharmacology of L-type Calcium Channels: Novel Drugs for Old Targets?

Authors: Jörg Striessnig; Nadine J Ortner; Alexandra Pinggera
Journal: Curr Mol Pharmacol Date: 2015 Impact factor: 3.339

Review 6. The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic Potential.

Authors: Gerald W Zamponi; Joerg Striessnig; Alexandra Koschak; Annette C Dolphin
Journal: Pharmacol Rev Date: 2015-10 Impact factor: 25.468

Structural basis for pore blockade of human voltage-gated calcium channel Ca_v1.3 by motion sickness drug cinnarizine.

Review 1. Structure and regulation of voltage-gated Ca2+ channels.

Review 2. The ß subunit of voltage-gated Ca2+ channels.

3. A Single Amino Acid Determines the Selectivity and Efficacy of Selective Negative Allosteric Modulators of Ca_V1.3 L-Type Calcium Channels.

4. Closed-state inactivation and pore-blocker modulation mechanisms of human Ca_V2.2.

Review 5. Pharmacology of L-type Calcium Channels: Novel Drugs for Old Targets?

Review 6. The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic Potential.

7. Structure of human Ca_v2.2 channel blocked by the painkiller ziconotide.

8. Modest CaV1.342-selective inhibition by compound 8 is β-subunit dependent.

9. Structural Basis of the Modulation of the Voltage-Gated Calcium Ion Channel Ca_v 1.1 by Dihydropyridine Compounds*.

10. Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators.

Structural basis for pore blockade of human voltage-gated calcium channel Cav1.3 by motion sickness drug cinnarizine.

Review 1. Structure and regulation of voltage-gated Ca2+ channels.

Review 2. The ß subunit of voltage-gated Ca2+ channels.

3. A Single Amino Acid Determines the Selectivity and Efficacy of Selective Negative Allosteric Modulators of CaV1.3 L-Type Calcium Channels.

4. Closed-state inactivation and pore-blocker modulation mechanisms of human CaV2.2.

Review 5. Pharmacology of L-type Calcium Channels: Novel Drugs for Old Targets?

Review 6. The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic Potential.

7. Structure of human Cav2.2 channel blocked by the painkiller ziconotide.

8. Modest CaV1.342-selective inhibition by compound 8 is β-subunit dependent.

9. Structural Basis of the Modulation of the Voltage-Gated Calcium Ion Channel Cav 1.1 by Dihydropyridine Compounds*.

10. Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators.

Structural basis for pore blockade of human voltage-gated calcium channel Ca_v1.3 by motion sickness drug cinnarizine.

3. A Single Amino Acid Determines the Selectivity and Efficacy of Selective Negative Allosteric Modulators of Ca_V1.3 L-Type Calcium Channels.

4. Closed-state inactivation and pore-blocker modulation mechanisms of human Ca_V2.2.

7. Structure of human Ca_v2.2 channel blocked by the painkiller ziconotide.

9. Structural Basis of the Modulation of the Voltage-Gated Calcium Ion Channel Ca_v 1.1 by Dihydropyridine Compounds*.