| Literature DB >> 35473717 |
Päivi Kolu1, Jaana T Kari2, Jani Raitanen3,4, Harri Sievänen3,4, Kari Tokola3, Eino Havas5, Jaakko Pehkonen2, Tuija H Tammelin5, Katja Pahkala6,7,8, Nina Hutri-Kähönen9, Olli T Raitakari6,8,10, Tommi Vasankari3,11.
Abstract
BACKGROUND: Low physical activity and high sedentary behaviour are unquestionably relevant for public health while also increasing direct and indirect costs.Entities:
Keywords: economics; epidemiology; health promotion; public health; sick leave
Mesh:
Year: 2022 PMID: 35473717 PMCID: PMC9209672 DOI: 10.1136/jech-2021-217998
Source DB: PubMed Journal: J Epidemiol Community Health ISSN: 0143-005X Impact factor: 6.286
Variables and register-based data sets employed in the cost estimations in different age groups
| Variable | Data set and data-collection year | Age range (years) |
|
| ||
| Accelerometer-measured physical activity | FINFIT 2017 (Finnish population study) | 20–69 |
| Accelerometer-measured sedentary behaviour | FINFIT 2017 (Finnish population study) | 20–69 |
| Self-reported physical activity | Cardiovascular Risk in Young Finns Study (1980–1992) | 15 |
|
| ||
| Non-communicable diseases* | Hospital-discharge register, 2016 | All |
| Institutional eldercare† | Hospital-discharge register for social welfare, 2016 | ≥65 |
|
| ||
| Sickness-related absences and disability pension‡ | Social Insurance Institution of Finland, 2017 | 15–64 |
| All-cause mortality | Causes of Death, 2016 | 15–64 |
| Unemployment benefits | Finnish Longitudinal Employer–Employee Data (FLEED), 2005–2012 | 28–47 |
| Income taxes | FLEED, 2005–2012 | 28–47 |
*Includes coronary heart disease, type 2 diabetes, breast cancer, colon cancer, stroke, depression (mild and moderate), fracture (proximal humerus, distal radius and hip) and back disorders (visits to a primary care physician).
†Includes Alzheimer’s disease, hip fracture and stroke.
‡Includes coronary heart disease, type 2 diabetes, breast cancer, colon cancer, stroke, depression, fracture and back disorders.
Adjusted relative risks (RR) for non-communicable diseases that is attributable to low physical activity and high sedentary behaviour reported in studies of physical inactivity, institutional eldercare and sedentary behaviour
| Study/reference | RR (95% Cl) | Adjustment factor* | |
|
| |||
| Coronary heart disease | Lee | 1.16 (1.04 to 1.30) | 1.20 |
| Type 2 diabetes | Lee | 1.20 (1.10 to 1.33) | 1.23 |
| Breast cancer | Lee | 1.33 (1.26 to 1.42) | 1.05 |
| Colon cancer | Lee | 1.32 (1.23 to 1.39) | 1.22 |
| Stroke | Ding | 1.18 (NA) | 1.40† |
| Depression | Schuch | 1.19 (1.13 to 1.26)‡ | NA |
| Back pain | Shiri and Falah-Hasani | 1.12 (1.03 to 1.22) | NA |
| Fracture | Qu | 1.41 (1.25 to 1.59) | NA |
| All-cause mortality | Lee | 1.28 (1.21 to 1.36) | 1.22 |
|
| |||
| Alzheimer’s disease | Beckett | 1.64 (1.37 to 1.92) | NA |
| Fracture | Qu | 1.41 (1.25 to 1.59) | NA |
| Stroke | Ding | 1.18 (NA) | 1.40 |
|
| |||
| Coronary heart disease | Petersen | 1.12 (0.95 to 1.28)§ | 1.23 |
| Type 2 diabetes | Heron | 1.88 (1.62 to 2.17) | 1.12 |
| All-cause mortality | Heron | 1.25 (1.16 to 1.34) | 1.87 |
| Colon cancer | Heron | 1.30 (1.12 to 1.49) | 1.22 |
| Breast cancer | Shen | 1.17 (1.03 to 1.33) | NA |
| Depression | Zhai | 1.14 (1.06 to 1.21) | NA |
*Adjustment factor was used to explore differences in physical activity and sedentary behaviour between cases with non-communicable disease of interest and healthy participants: If not reported for the cases, physical acitivity was derived from the entire study population.7
†From Finnish (FINRISK) cohort study.
‡OR.
§Pooled HR.
NA, not available.
Mean direct and indirect costs associated with low physical activity (of 77% of adults) and high sedentary behaviour (83%), in millions of euros, except unemployment benefits and income tax or earnings-tax contributions (cited as per-individual costs in euros and were converted to values in 2017)
| Cost (in millions of euros) of low physical activity (95% CI)* | Cost (in millions of euros) of | |
|
| ||
| Use of healthcare services | 214.1 (137.4 to 292.9) | 346.3 (253.3 to 421.8) |
| Medications | 49.1 (28.2 to 71.5) | 122.9 (97.9 to 143.7) |
| Institutional eldercare | 419.4 (306.2 to 504.3) | – |
| | 682.6 (471.8 to 868.7) | 469.2 (351.2 to 565.4) |
| Indirect costs | ||
| Short sickness-related absence (≤10 days)† | 11.3 (6.5 to 15.8) | 2.3 (0.5 to 3.8) |
| Long sickness-related absence (>10 days)† | 44.4 (29.3 to 59.3) | 42.6 (27.4 to 54.9) |
| Disability pension† | 324.9 (187.5 to 469.9) | 691.3 (542.2 to 813.0) |
| All-cause mortality† | 300.1 (238.1 to 363.1) | 298.1 (205.6 to 378.1) |
| Income taxes§ | 1843.7 (639.0 to 3005.8) | – |
| Unemployment benefits § | 21.2 (4.3 to 38.1) | – |
| | 2545.5 (1104.7 to 3952.0) | 1034.3 (775.7 to 1249.8) |
| Total costs | 3228.1 (1576.5 to 4820.7) | 1503.5 (1126.9 to 1815.2) |
*CIs are based on the lower and upper relative risk level, excluding unemployment benefits and income tax.
†Costs related to non-communicable diseases.
‡Total costs (excluding income taxes and unemployment benefits)= , that is, total annual costs were obtained by multiplying the population attributable fraction by the total costs of the relevant disease.
§The results are based on ordinary least squares regression (see online supplemental material 1) in which the reference category is being physically active. Models include controls for gender, birth cohort, birth month, an individual’s chronic diseases, body fat, education level, employment status, parents’ education, parents’ physical activity, family income and family size.