| Literature DB >> 35469111 |
August Eubanks1, Bakary Coulibaly2, Bintou Dembélé Keita2, Camille Anoma3, Ter Tiero Elias Dah4,5, Ephrem Mensah6, Gwenaëlle Maradan7,8, Michel Bourrelly7,9, Marion Mora7, Lucas Riegel9, Daniela Rojas Castro7,9, Issifou Yaya10, Bruno Spire7, Christian Laurent10, Luis Sagaon-Teyssier7,2.
Abstract
We investigated the rate and predictors of ineffective HIV protection in men who have sex with men (MSM) taking pre-exposure prophylaxis (PrEP) in a prospective cohort study from November 2017 to November 2020 in Mali, Côte d'Ivoire, Burkina Faso, and Togo. MSM had to be 18 years or older and at high risk of HIV infection to participate. They also received a comprehensive sexual health prevention package, including PrEP, in community-based clinics as part of the cohort study. Using socio-behavioral/clinical data, HIV protection during their most recent anal intercourse with a male partner was categorized as effective or ineffective (i.e., incorrect PrEP adherence and no condom use). Seventeen percent (500/2839) of intercourses were ineffectively protected for the 520 study participants. Predictors of ineffective HIV protection included being an event-driven user with financial difficulties, having a high alcohol misuse score, and not being a member of a community association. PrEP programs in West Africa must be tailored to socially vulnerable MSM who struggle to adopt PrEP.Entities:
Keywords: Community-based research; HIV; MSM; PrEP; West Africa
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Year: 2022 PMID: 35469111 DOI: 10.1007/s10461-022-03692-8
Source DB: PubMed Journal: AIDS Behav ISSN: 1090-7165