Literature DB >> 35468811

Correction to: Mical modulates Tau toxicity via cysteine oxidation in vivo.

Engie Prifti1,2, Eleni N Tsakiri1, Ergina Vourkou1, George Stamatakis3, Martina Samiotaki3, Efthimios M C Skoulakis1, Katerina Papanikolopoulou4.   

Abstract

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Year:  2022        PMID: 35468811      PMCID: PMC9040322          DOI: 10.1186/s40478-022-01369-w

Source DB:  PubMed          Journal:  Acta Neuropathol Commun        ISSN: 2051-5960            Impact factor:   7.801


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Correction to: Acta Neuropathologica Communications (2022) 10:44 10.1186/s40478-022-01348-1

Following publication of the original article [1], it was noted that due to a typesetting mistake, incorrect files for Additional files 6 and 7 were processed. The correct files for Additional files 6 and 7 are attached to this Correction and have been corrected in the original article. The publisher apologises to the authors and readers for the inconvenience caused by this error. Additional file 6: Fig. S5 Targeted proteomics to quantify cysteine oxidation. a Extracted chromatograms for the parent ions and isotopes (upper panel) and of its 6 most abundant fragments (daughter ions, lower panel) at the retention time 27.9 min of the NEM and carbamidomethyl labeled 322CGSLGNIHHKPGGGQVEVK peptide from representative samples of Tau and Tau co-overexpressed with Mical. b Spectra of the scan used for the library creation of the NEM (+ 125 Da) and carbamidomethyl (+ 57 Da) modified 322CGSLGNIHHKPGGGQVEVK peptide. Additional file 7: Fig. S6 a Representative Western blot of head lysates from flies expressing UAS-htauFLAG−2N4RC322A using elav-GAL4;Ras2-GAL4 and UAS-htauFLAG−2N4RC291A using elav-GAL4. Star indicates significant differences between the two groups. b Virgin elav-GAL4;Ras2-GAL4 females were crossed with UAS-Mic/CyO and UAS-Mic/CyO;UAS-C322A males. Bars represent the mean number of non-CyO bearing progeny over CyO flies ± SEM of the indicated genotypes. c Response of flies expressing UAS-htauFLAG−2N4RC291A upon treatment with paraquat for 28 h. Star indicates significant difference from the transgene without Mical overexpression. Control flies are elav-GAL4/+ (grey bar) and Mical are flies that overexpress Mical under the panneuronal driver (black bar). d Memory performance of animals expressing panneuronally the htauFLAG−2N4RC291A transgene (dark grey bar), compared with the same transgene upon co-expression with Mical (black bar). Star indicates significant difference between the two genotypes. Control flies (light grey bars) are driver elav-GAL4/+ flies (CN) and flies that overexpress Mical. The number of experimental replicates (n) is indicated within the bars.
  1 in total

1.  Mical modulates Tau toxicity via cysteine oxidation in vivo.

Authors:  Engie Prifti; Eleni N Tsakiri; Ergina Vourkou; George Stamatakis; Martina Samiotaki; Efthimios M C Skoulakis; Katerina Papanikolopoulou
Journal:  Acta Neuropathol Commun       Date:  2022-04-04       Impact factor: 7.801

  1 in total

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