Literature DB >> 35467276

Detection of Cancer-Derived Exosomes Using a Sensitive Colorimetric Aptasensor.

Lizhou Xu1,2, Khuloud T Al-Jamal3.   

Abstract

Exosomes are a type of extracellular vesicles that contain constituents including proteins, DNAs, and RNAs of the cells that secrete them. Cancerous exosomes are potential biomarkers for cancer diagnosis. Biosensors are useful analytical tools for quantification of biomarkers and targeted molecules. An aptasensor uses the aptamer as the biorecognition element to bind to the target and is one main type of biosensors that is promising for exosomes analysis and clinical cancer detection. The assay described in this chapter allows for reliable, sensitive, and specific detection of cancer-derived exosomes using a colorimetric aptasensor that is promising for point-of-care testing.
© 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Aptamer; Aptasensor; Biomarker; Biosensor; Cancer detection; Exosomes

Mesh：

Substances：

Year:  2022        PMID： 35467276     DOI： 10.1007/978-1-0716-2341-1_2

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  16 in total

Review 1.  Exosomes: composition, biogenesis and function.

Authors:  Clotilde Théry; Laurence Zitvogel; Sebastian Amigorena
Journal:  Nat Rev Immunol       Date:  2002-08       Impact factor: 53.106

2.  Biosensors for rapid detection of Salmonella in food: A review.

Authors:  Yafang Shen; Lizhou Xu; Yanbin Li
Journal:  Compr Rev Food Sci Food Saf       Date:  2020-11-11       Impact factor: 12.811

3.  SnapShot: Extracellular Vesicles.

Authors:  Federico Cocozza; Eleonora Grisard; Lorena Martin-Jaular; Mathilde Mathieu; Clotilde Théry
Journal:  Cell       Date:  2020-07-09       Impact factor: 41.582

Review 4.  The biology, function, and biomedical applications of exosomes.

Authors:  Raghu Kalluri; Valerie S LeBleu
Journal:  Science       Date:  2020-02-07       Impact factor: 47.728

5.  Capacitive aptasensor based on interdigitated electrode for breast cancer detection in undiluted human serum.

Authors:  Sunil K Arya; Pavel Zhurauski; Pawan Jolly; Marina R Batistuti; Marcelo Mulato; Pedro Estrela
Journal:  Biosens Bioelectron       Date:  2017-11-08       Impact factor: 10.618

Review 6.  Optical, electrochemical and electrical (nano)biosensors for detection of exosomes: A comprehensive overview.

Authors:  Lizhou Xu; Nahid Shoaie; Fatemeh Jahanpeyma; Junjie Zhao; Mostafa Azimzadeh; Khuloud T Al Jamal
Journal:  Biosens Bioelectron       Date:  2020-04-21       Impact factor: 10.618

7.  Development of a Highly Sensitive Device for Counting the Number of Disease-Specific Exosomes in Human Sera.

Authors:  Yasuaki Kabe; Makoto Suematsu; Satoshi Sakamoto; Miwa Hirai; Ikko Koike; Takako Hishiki; Atsushi Matsuda; Yuichi Hasegawa; Koji Tsujita; Masayuki Ono; Naoko Minegishi; Atsushi Hozawa; Yoshinori Murakami; Michiaki Kubo; Makoto Itonaga; Hiroshi Handa
Journal:  Clin Chem       Date:  2018-07-18       Impact factor: 8.327

8.  Reassessment of Exosome Composition.

Authors:  Dennis K Jeppesen; Aidan M Fenix; Jeffrey L Franklin; James N Higginbotham; Qin Zhang; Lisa J Zimmerman; Daniel C Liebler; Jie Ping; Qi Liu; Rachel Evans; William H Fissell; James G Patton; Leonard H Rome; Dylan T Burnette; Robert J Coffey
Journal:  Cell       Date:  2019-04-04       Impact factor: 41.582

Review 9.  The evolving translational potential of small extracellular vesicles in cancer.

Authors:  Andreas Möller; Richard J Lobb
Journal:  Nat Rev Cancer       Date:  2020-09-21       Impact factor: 60.716

Review 10.  Facile biosensors for rapid detection of COVID-19.

Authors:  Lizhou Xu; Danyang Li; Sami Ramadan; Yanbin Li; Norbert Klein
Journal:  Biosens Bioelectron       Date:  2020-10-01       Impact factor: 10.618
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