Literature DB >> 3546710

Hypertrophic skin grafts in burned patients: a prospective analysis of variables.

W S McDonald, E A Deitch.   

Abstract

A prospective study of 70 consecutive burned patients, 26 pediatric patients and 44 adults, who had 173 separate anatomic sites grafted, was carried out to determine the incidence of hypertrophic skin grafts after thermal injury. The age, race, postburn day grafted, anatomic site grafted, and nature of the recipient graft bed was recorded. The patients were followed for a minimum of 1 year, at which time the skin grafts were classified as Excellent (E)--skin graft flat and not thickened; Good (G)--less than 5% of skin graft thickened or elevated; Fair (F)--greater than 5% of skin graft thickened or elevated; and Poor (P)--skin graft elevated greater than 2 mm or contracture present. Overall, 55% of the grafted sites were excellent, 18% were good, 13% were fair, and 14% were poor. Pediatric patients had a higher incidence of fair or poor results (50%) than adults (17%) (p less than 0.001), and blacks had poorer (39% F or P) results than whites (12% F or P) (p less than 0.001). The presence of dermal elements in the recipient graft bed was associated with less long-term skin graft scarring than when the grafts were placed on recipient beds without dermal elements (p less than 0.01). Skin grafts that were performed within 14 days of the injury had a lower incidence of F or P results (24%), than grafts performed after 14 days postburn (37%) (p less than 0.03). Based on the results of this prospective study, it is possible to identify and quantitate the relative risk of a burned patient developing a hypertrophic skin graft.

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Year:  1987        PMID: 3546710     DOI: 10.1097/00005373-198702000-00008

Source DB:  PubMed          Journal:  J Trauma        ISSN: 0022-5282


  14 in total

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Journal:  Aesthetic Plast Surg       Date:  2021-05-10       Impact factor: 2.326

2.  Activated keratinocytes in the epidermis of hypertrophic scars.

Authors:  M Machesney; N Tidman; A Waseem; L Kirby; I Leigh
Journal:  Am J Pathol       Date:  1998-05       Impact factor: 4.307

3.  The cost of post-burn scarring.

Authors:  U Mirastschijski; J T Sander; U Zier; H O Rennekampff; B Weyand; P M Vogt
Journal:  Ann Burns Fire Disasters       Date:  2015-09-30

4.  Comparison of the Results of Early Excision and Grafting between Children and Adults; A Prospective Comparative Study.

Authors:  Mehdi Ayaz; Abdolkhalegh Keshavarzi; Hamid Bahadoran; Peyman Arasteh; Sam Moslemi
Journal:  Bull Emerg Trauma       Date:  2017-07

5.  Anomalous expression of HLA class II molecules on keratinocytes and fibroblasts in hypertrophic scars consequent to thermal injury.

Authors:  C Castagnoli; M Stella; G Magliacani; S T Alasia; P Richiardi
Journal:  Clin Exp Immunol       Date:  1990-11       Impact factor: 4.330

6.  The role of the TGF-β family in wound healing, burns and scarring: a review.

Authors:  Jack W Penn; Adriaan O Grobbelaar; Kerstin J Rolfe
Journal:  Int J Burns Trauma       Date:  2012-02-05

7.  Predicting severity of pathological scarring due to burn injuries: a clinical decision making tool using Bayesian networks.

Authors:  Paola Berchialla; Ezio Nicola Gangemi; Francesca Foltran; Arber Haxhiaj; Alessandra Buja; Fulvio Lazzarato; Maurizio Stella; Dario Gregori
Journal:  Int Wound J       Date:  2012-09-07       Impact factor: 3.315

8.  Adolescents with and without head and neck burns: comparison of long-term outcomes in the burn model system national database.

Authors:  Benjamin B Wang; Khushbu F Patel; Audrey E Wolfe; Shelley Wiechman; Kara McMullen; Nicole S Gibran; Karen Kowalske; Walter J Meyer; Lewis E Kazis; Colleen M Ryan; Jeffrey C Schneider
Journal:  Burns       Date:  2021-04-20       Impact factor: 2.744

9.  Hypertrophic scarring in cleft lip repair: a comparison of incidence among ethnic groups.

Authors:  Ali M Soltani; Cameron S Francis; Arash Motamed; Ashley L Karatsonyi; Jeffrey A Hammoudeh; Pedro A Sanchez-Lara; John F Reinisch; Mark M Urata
Journal:  Clin Epidemiol       Date:  2012-07-26       Impact factor: 4.790

10.  Functional genomics unique to week 20 post wounding in the deep cone/fat dome of the Duroc/Yorkshire porcine model of fibroproliferative scarring.

Authors:  Loren H Engrav; Christopher K Tuggle; Kathleen F Kerr; Kathy Q Zhu; Surawej Numhom; Oliver P Couture; Richard P Beyer; Anne M Hocking; Gretchen J Carrougher; Maria Luiza C Ramos; Matthew B Klein; Nicole S Gibran
Journal:  PLoS One       Date:  2011-04-20       Impact factor: 3.240

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