Literature DB >> 35463547

Current practice of antibiotic prophylaxis in elective laparoscopic cholecystectomy among surgeons of the Armed Forces Medical Services of India.

Ameet Kumar1, Sumesh Kaistha2.   

Abstract

Background: Laparoscopic cholecystectomy (LC) is the most common surgery done in general surgical practice worldwide. Despite clear guidelines recommending against the routine use of antibiotic prophylaxis (ABP) for elective LC by professional entities such as the Scottish Intercollegiate Guidelines Network (SIGN), Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) etc., most surgeons are not convinced about omitting ABP in low-risk LC. Thus, this study aimed at capturing the practice of administering ABP in elective LC among surgeons of Armed Forces Medical Services (AFMS).
Methods: This was a survey based on an electronic, cross-sectional, self-completion questionnaire that was designed and disseminated amongst 184 surgeons of the AFMS, online, and the data was collated centrally.
Results: 64% of surgeons completed the survey. The majority (85%) of surgeons used ABP routinely in elective LC. In the univariate analysis, only the number of years of surgical experience and the total number of LC done in an entire career, and in the multivariate analysis age group of the surgeon, surgical experience and designation were significant factors for avoiding routine ABP in elective LC. Amongst the surgeons administering ABP, only 30% administered a single dose, 73% chose a single agent and Cefotaxime (57%) was the commonest antibiotic used.
Conclusion: This study found that there is a high prevalence of use of antibiotic prophylaxis in elective laparoscopic cholecystectomy amongst the surgeons of the AFMS. There was a wide variation in terms of choice of antibiotics, administering single or multiple doses and as a single agent or combination therapy. Registered with clinical trials registry of India: CTRI/2019/03/018092.
© 2022 Director General, Armed Forces Medical Services. Published by Elsevier, a division of RELX India Pvt. Ltd.

Entities:  

Keywords:  Antibiotic prophylaxis; Cholecystectomy; Clean contaminated; Laparoscopic; Port site infection; Surgical site infection; Survey

Year:  2021        PMID: 35463547      PMCID: PMC9023552          DOI: 10.1016/j.mjafi.2020.12.014

Source DB:  PubMed          Journal:  Med J Armed Forces India        ISSN: 0377-1237


  18 in total

1.  SAGES guidelines for the clinical application of laparoscopic biliary tract surgery.

Authors:  D Wayne Overby; Keith N Apelgren; William Richardson; Robert Fanelli
Journal:  Surg Endosc       Date:  2010-08-13       Impact factor: 4.584

Review 2.  Safety and efficacy of antibiotic prophylaxis in patients undergoing elective laparoscopic cholecystectomy: A systematic review and meta-analysis.

Authors:  Bo Liang; Min Dai; Zhenhong Zou
Journal:  J Gastroenterol Hepatol       Date:  2016-05       Impact factor: 4.029

Review 3.  Role of prophylactic antibiotics in laparoscopic cholecystectomy: a meta-analysis.

Authors:  Abhishek Choudhary; Matthew L Bechtold; Srinivas R Puli; Mohamed O Othman; Praveen K Roy
Journal:  J Gastrointest Surg       Date:  2008-09-09       Impact factor: 3.452

4.  A national audit of antibiotic prophylaxis in elective laparoscopic cholecystectomy.

Authors:  H E Graham; A Vasireddy; D Nehra
Journal:  Ann R Coll Surg Engl       Date:  2014-07       Impact factor: 1.891

5.  Role of Prophylactic Antibiotics in Laparoscopic Cholecystectomy.

Authors:  A Gaur; A K Pujahari
Journal:  Med J Armed Forces India       Date:  2011-07-21

6.  The role of prophylactic antibiotics in laparoscopic cholecystectomy in preventing postoperative infection: a meta-analysis.

Authors:  Rui-Cheng Yan; Shi-Qiang Shen; Zu-Bing Chen; Fu-Sheng Lin; Jan Riley
Journal:  J Laparoendosc Adv Surg Tech A       Date:  2011-03-28       Impact factor: 1.878

Review 7.  Antibiotic prophylaxis for patients undergoing elective laparoscopic cholecystectomy.

Authors:  Alvaro Sanabria; Luis C Dominguez; Eduardo Valdivieso; Gabriel Gomez
Journal:  Cochrane Database Syst Rev       Date:  2010-12-08

8.  The relationship between antimicrobial resistance and patient outcomes: mortality, length of hospital stay, and health care costs.

Authors:  Sara E Cosgrove
Journal:  Clin Infect Dis       Date:  2006-01-15       Impact factor: 9.079

9.  Antibiotic Prophylaxis in Elective Laparoscopic Cholecystectomy: a Systematic Review and Network Meta-Analysis.

Authors:  Juan Camilo Gomez-Ospina; James A Zapata-Copete; Monica Bejarano; Herney Andrés García-Perdomo
Journal:  J Gastrointest Surg       Date:  2018-03-19       Impact factor: 3.452

Review 10.  Meta-analysis of perioperative antibiotics in patients undergoing laparoscopic cholecystectomy.

Authors:  S Pasquali; M Boal; E A Griffiths; D Alderson; R S Vohra
Journal:  Br J Surg       Date:  2015-09-02       Impact factor: 6.939

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