Meta-analysis of prognostic factors related to early urinary incontinence following new transurethral procedures dominated by laser therapy for benign prostatic hyperplasia.

To investigate the predictors of early postoperative UI after new minimally transurethral procedures dominated by laser therapy for benign prostatic hyperplasia. A literature review of articles published before June 30, 2021 was conducted using the PubMed, Web of Sciences, Cochrane database, and Embase databases. All studies reporting odds ratio (OR) data of prognostic factors in univariable or multivariable analyses were included. The cutoff points of follow-up were within 1 month, at 3 months, and at 6 months. Fourteen studies were identified and assessed for the meta-analysis. The pooled analysis yielded that three prognostic factors related to postoperative urinary incontinence. The pooled OR for age as a continuous variable was 1.066 (95% CI 1.005-1.031) at 3 months, the pooled OR was 3.7 (95% CI 1.276-10.733) for age as a categorical variable within 1 month. The OR for prostate volume was 1.014 (95% CI 1.002-1.026) within 1 month. The pooled OR for prostate volume as a categorical variable was 2.199 (95% CI 1.038-4.659) at 3 months. The OR for resected prostate weight was 1.008 (95% CI 1.001-1.016) within 1 month and the pooled OR for resected prostate weight as a categorical variable was 3.481 (95% CI 1.674-7.239) at 3 months. For patients who have undergone transurethral surgery of prostate using new minimally invasive method, especially laser-based therapy, main factors influencing the development of postoperative UI within 1 month and at 3 months were age, prostate volume, and resected prostate weight.